ID B7YZS4_DROME Unreviewed; 1842 AA.
AC B7YZS4;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=Calmodulin-binding transcription activator, isoform E {ECO:0000313|EMBL:ACL83080.1};
GN Name=Camta {ECO:0000313|EMBL:ACL83080.1,
GN ECO:0000313|FlyBase:FBgn0287478};
GN Synonyms=camta {ECO:0000313|EMBL:ACL83080.1}, CG13952
GN {ECO:0000313|EMBL:ACL83080.1}, CG13953 {ECO:0000313|EMBL:ACL83080.1},
GN CG8809 {ECO:0000313|EMBL:ACL83080.1}, cro
GN {ECO:0000313|EMBL:ACL83080.1}, dCAMTA {ECO:0000313|EMBL:ACL83080.1},
GN DmCAMTA {ECO:0000313|EMBL:ACL83080.1}, Dmel\CG42332
GN {ECO:0000313|EMBL:ACL83080.1};
GN ORFNames=CG42332 {ECO:0000313|EMBL:ACL83080.1,
GN ECO:0000313|FlyBase:FBgn0287478}, Dmel_CG42332
GN {ECO:0000313|EMBL:ACL83080.1};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227 {ECO:0000313|EMBL:ACL83080.1, ECO:0000313|Proteomes:UP000000803};
RN [1] {ECO:0000313|EMBL:ACL83080.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A.,
RA An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H.,
RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E.,
RA Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C.,
RA Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A.,
RA Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C.,
RA Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G.,
RA Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.,
RA Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2] {ECO:0000313|EMBL:ACL83080.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537568;
RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A.,
RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A.,
RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R.,
RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J.,
RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C.,
RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.;
RT "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster
RT euchromatic genome sequence.";
RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002).
RN [3] {ECO:0000313|EMBL:ACL83080.1, ECO:0000313|Proteomes:UP000000803}
RP GENOME REANNOTATION.
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [4] {ECO:0000313|EMBL:ACL83080.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537573;
RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R.,
RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M.,
RA Celniker S.E.;
RT "The transposable elements of the Drosophila melanogaster euchromatin: a
RT genomics perspective.";
RL Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002).
RN [5] {ECO:0000313|EMBL:ACL83080.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537574;
RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A.,
RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G.,
RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M.,
RA Karpen G.H.;
RT "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.";
RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002).
RN [6] {ECO:0000313|EMBL:ACL83080.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022;
RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D.,
RA Ashburner M., Anxolabehere D.;
RT "Combined evidence annotation of transposable elements in genome
RT sequences.";
RL PLoS Comput. Biol. 1:166-175(2005).
RN [7] {ECO:0000313|EMBL:ACL83080.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=17569856; DOI=10.1126/science.1139815;
RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.;
RT "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.";
RL Science 316:1586-1591(2007).
RN [8] {ECO:0000313|EMBL:ACL83080.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=17569867; DOI=10.1126/science.1139816;
RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M.,
RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A.,
RA Dimitri P., Karpen G.H., Celniker S.E.;
RT "Sequence finishing and mapping of Drosophila melanogaster
RT heterochromatin.";
RL Science 316:1625-1628(2007).
CC -!- SUBUNIT: May interact with calmodulin. {ECO:0000256|ARBA:ARBA00029480}.
CC -!- SIMILARITY: Belongs to the CAMTA family.
CC {ECO:0000256|ARBA:ARBA00008267}.
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DR EMBL; AE013599; ACL83080.1; -; Genomic_DNA.
DR RefSeq; NP_001137626.1; NM_001144154.2.
DR SMR; B7YZS4; -.
DR EnsemblMetazoa; FBtr0299847; FBpp0289125; FBgn0287478.
DR GeneID; 35974; -.
DR AGR; FB:FBgn0287478; -.
DR CTD; 35974; -.
DR FlyBase; FBgn0287478; Camta.
DR VEuPathDB; VectorBase:FBgn0287478; -.
DR GeneTree; ENSGT00940000165359; -.
DR OrthoDB; 470813at2759; -.
DR PhylomeDB; B7YZS4; -.
DR BioGRID-ORCS; 35974; 0 hits in 3 CRISPR screens.
DR ChiTaRS; Camta; fly.
DR GenomeRNAi; 35974; -.
DR Proteomes; UP000000803; Chromosome 2R.
DR ExpressionAtlas; B7YZS4; baseline and differential.
DR Genevisible; B7YZS4; DM.
DR GO; GO:0005634; C:nucleus; IDA:FlyBase.
DR GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0003712; F:transcription coregulator activity; IBA:GO_Central.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0016059; P:deactivation of rhodopsin mediated signaling; IMP:FlyBase.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005559; CG-1_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23335; CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA; 1.
DR PANTHER; PTHR23335:SF0; CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR, ISOFORM F; 1.
DR Pfam; PF03859; CG-1; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM01076; CG-1; 1.
DR SMART; SM00015; IQ; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51437; CG_1; 1.
DR PROSITE; PS50096; IQ; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW Reference proteome {ECO:0000313|Proteomes:UP000000803};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT DOMAIN 255..380
FT /note="CG-1"
FT /evidence="ECO:0000259|PROSITE:PS51437"
FT REGION 119..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 734..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 789..857
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 877..950
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 980..1016
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1397..1416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1562..1596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1736..1765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1819..1842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..204
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 792..857
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 980..1010
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1399..1416
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1562..1585
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1842 AA; 204108 MW; F25C467D780D0E34 CRC64;
MAGYRSLPLA PVAATAAVQP TMGGVPPTMA AYAHHQSMTA MSNNGIIYQS AVHASIHSLN
TVQSQHRSST TTHHHILATA TATATATAAA AAATATAAAA AAAAVVALPT AAATAAAPQQ
HAAYGQQQPQ QHLQSQHQQQ QHLGQHHTQQ HSQQHAQQQQ QLMTHQQHSV AQQQHHHLQQ
QQHLQQQQQQ HHHHHHHHHH QQLSLHQNHL YFSGASLGHH HHHRQIFSHL QSALMPLSVN
GEPIKLPDNL ESLPRADSFP SQRHRWNTNE EIAAILISFD KHGEWQSKEV RTRPKSGSLL
LYSRKKVRYR RDGYCWKKRK DGKTTREDHM KLKVQGTECI YGCYVHSAIL PTFHRRCYWL
LQNPDIVLVH YLNVPYPDDN KMAVIAPSIT LWGDKKEWTK EELVSQLKPM LSTINSDDDS
DSGNDIEIST AETVESIVCQ LMEKQRLSRQ AALVKQLDCG CGDGGCVDGK TCTHPVMRRS
AAMLKSSVQE KRLGEPFNGN TPNVVVASKL YSRWAERPRQ HVDNHGQFHN VTQQLPQESA
IKFQIIPPQQ QQQQDGNYQQ QQYRGGSQML AARSNLVMQQ QQQHQQQQQY HQQQQQQQQQ
QQQHQQQQQH LSLQRFVASQ GQNSVHLNQQ HRLQIANTTI TATASDPATT LAAAAAVAAA
SGATPVALNI MDTELIENQN HMTANKITNS GSSNSSSSNA SKQLAGQTNN KLNVVNNNDP
GNNNFMYNQQ QQLNASSNSN NSSQQQQQQQ QQHYYKLQQT TATPTSGQPP PLAQVQPHSL
AQPPVEAMCM SPEHRSSSQP TPATSSAGSI PSSVSVSISV STSTPTPAPT SISTPTSGTS
STSSSLQSII DGNQQQQITT TSTAATCDNL MSANALSEQD SHTVNNQATE APNRSQLQSQ
SQSLSLNQNG CATYSASSDN SSQISDESSS FGGNNQNSSN SSTSEEEPQV EALSFFNETL
DLSQEDIQRT LIANMPYNTT AAGATAPSTT ITTGNTKLEL SQQETKEKPA MGTETATEIE
DDETDDVFAN LDAFDMLVEF PELDLDDKQA LNNTALEQSS FLGESAPSQP RKVHNICDFS
PEWSYTEGGV KVLVAGPWTS SNGGAYTVLF DAQPVPTQLV QEGVLRCYCP AHEAGFVTLQ
VACGGFLVSN SVMFEYKLSL LADAPFDATS SNDCLYKFTL LNRLSTIDEK LQVKTEHELT
TDNTALYLEP NFEEKLVAYC HKLIKHAWSM PSTAASWTVG LRGMTLLHLA AALGYAKLVG
AMLNWRSENP HIILETELDA LSQDVYGFTP LAWACVRGHV ECSLLLYKWN HNALKIKTQA
QQTPLDLASM RGHKVLLAQM YRLEKERCRK PQLRGGLANL SMNMGVEAEA EEQHQSFSAF
DLELQRKHDG VFLRPVAVHS NQSPPNGSSR YSKRSSIDSG INMDIRSKSG KPLARLHSNF
ESHDSYALGV DSPLDSLTGT NCLLSPLRKM DFALWDSDAK VLTLAEHIIA AMPERIKNEA
DEMMVLGSPL TEPLTSESSA LTDSFMDPLL DSLPNTHFDS DFSFDFHDHS YRYHDVSTPC
SSLSPASSGP LQSPASYSIL GTDPSVSSPS PPPSTKQLTE FLHASSISSY PFEADFSKLT
LTDTEQRELY EAAKCIQKAY RSYKGRQKLE EQNKERSAAT VIQNYYRRYK QYAYYRQMTN
AALVIQHGYR SYRRNKRFKK SGLCLSSSSD HGSVSSNSQC LSSFYDHYKQ DQQQLHELGS
QPSTPKETSP SGPLKRTYSQ STQNQAARKI QQFMRQSRIK LQKERAEKEK LVHQRRAEYL
QNLQFQGQQE MLVYHENNIS APSSGNTNAS NNNNLHQIQS NQ
//
