ID   B7Z277_HUMAN            Unreviewed;       283 AA.
AC   B7Z277;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 95.
DE   RecName: Full=Septin-10 {ECO:0000256|ARBA:ARBA00039309};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAH11763.1};
RN   [1] {ECO:0000313|EMBL:BAH11763.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Amygdala {ECO:0000313|EMBL:BAH11763.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A.,
RA   Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y.,
RA   Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.,
RA   Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; AK294427; BAH11763.1; -; mRNA.
DR   RefSeq; NP_001308428.1; NM_001321499.1.
DR   AlphaFoldDB; B7Z277; -.
DR   MaxQB; B7Z277; -.
DR   PeptideAtlas; B7Z277; -.
DR   ProteomicsDB; 6416; -.
DR   DNASU; 151011; -.
DR   GeneID; 151011; -.
DR   CTD; 151011; -.
DR   OrthoDB; 5396944at2759; -.
DR   BioGRID-ORCS; 151011; 10 hits in 1085 CRISPR screens.
DR   GenomeRNAi; 151011; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030379; G_SEPTIN_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016491; Septin.
DR   PANTHER; PTHR18884; SEPTIN; 1.
DR   PANTHER; PTHR18884:SF50; SEPTIN-10; 1.
DR   Pfam; PF00735; Septin; 1.
DR   PIRSF; PIRSF006698; Septin; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51719; G_SEPTIN; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          1..162
FT                   /note="Septin-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51719"
FT   COILED          200..256
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   283 AA;  33025 MW;  9051EF7C38DD4CCD CRC64;
     MASSEVARHL LFQSHMATKT TCMSSQGSDD EQIVNIIPVI AKADTVSKTE LQKFKIKLMS
     ELVSNGVQIY QFPTDDDTIA KVNAAMNGQL PFAVVGSMDE VKVGNKMVKA RQYPWGVVQV
     ENENHCDFVK LREMLICTNM EDLREQTHTR HYELYRRCKL EEMGFTDVGP ENKPVSVQET
     YEAKRHEFHG ERQRKEEEMK QMFVQRVKEK EAILKEAERE LQAKFEHLKR LHQEERMKLE
     EKRRLLEEEI IAFSKKKATS EIFHSQSFLA TGSNLRKDKD RKK
//