ID   B7Z2N5_HUMAN            Unreviewed;       803 AA.
AC   B7Z2N5;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   01-MAY-2013, entry version 26.
DE   SubName: Full=cDNA FLJ51840, highly similar to Alpha-actinin-2;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Brain;
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA   Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA   Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA   Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AK294906; BAH11921.1; -; mRNA.
DR   IPI; IPI01010507; -.
DR   UniGene; Hs.498178; -.
DR   ProteinModelPortal; B7Z2N5; -.
DR   STRING; B7Z2N5; -.
DR   PRIDE; B7Z2N5; -.
DR   HOVERGEN; HBG050453; -.
DR   NextBio; 35479039; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0051764; P:actin crosslink formation; IEA:InterPro.
DR   GO; GO:0051017; P:actin filament bundle assembly; IEA:InterPro.
DR   Gene3D; 1.10.238.10; -; 2.
DR   Gene3D; 1.10.418.10; -; 2.
DR   InterPro; IPR001589; Actinin_actin-bd_CS.
DR   InterPro; IPR026921; Alpha-actinin.
DR   InterPro; IPR001715; CH-domain.
DR   InterPro; IPR011992; EF-hand-like_dom.
DR   InterPro; IPR014837; EF-hand_Ca_insen.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR018159; Spectrin/alpha-actinin.
DR   InterPro; IPR002017; Spectrin_repeat.
DR   PANTHER; PTHR11915:SF47; PTHR11915:SF47; 1.
DR   Pfam; PF00307; CH; 1.
DR   Pfam; PF08726; efhand_Ca_insen; 1.
DR   Pfam; PF00435; Spectrin; 4.
DR   SMART; SM00033; CH; 1.
DR   SMART; SM00054; EFh; 2.
DR   SMART; SM00150; SPEC; 3.
DR   SUPFAM; SSF47576; Calponin-homology; 1.
DR   PROSITE; PS00020; ACTININ_2; 1.
DR   PROSITE; PS50021; CH; 2.
DR   PROSITE; PS50222; EF_HAND_2; 2.
PE   2: Evidence at transcript level;
KW   Actin-binding; Calcium; Repeat.
SQ   SEQUENCE   803 AA;  92949 MW;  99A90292FDFE4E34 CRC64;
     MRFHKIANVN KALDYIASKG VKLVSIGAEE IVDGNVKMTL GMIWTIILRF AIQDISVEET
     SAKEGLLLWC QRKTAPYRNV NIQNFHTSWK DGLGLCALIH RHRPDLIDYS KLNKDDPIGN
     INLAMEIAEK HLDIPKMLDA EDLVYTARPD ERAIMTYVSC YYHAFAGAQK AETAANRICK
     VLAANQENER LMEEYERLAS ELLEWIRRTI PWLENRTPEK TMQAMQKKLE DFRDYRRKHK
     PPKVQEKCQL EINFNTLQTK LRISNRPAFM PSEGKMVSDI AGAWQRLEQA EKGYEEWLLN
     EIRRLERLEH LAEKFRQKAS THETWAYGKE QILLQKDYES ASLTEVRALL RKHEAFESDL
     AAHQDRVEQI AAIAQELNVL DYHDAVNVND RCQKICDQWD RLGTLTQKRR EALERMEKLL
     ETIDQLHLEF AKRAAPFNNW MEGAMEDLQD MFIVHSIEEI QSLITAHEQF KATLPEADGE
     RQSIMAIQNE VEKVIQSYNI RISSSNPYST VTMDELRTKW DKVKQLVPIR DQSLQEELAR
     QHANERLRRQ FAAQANAIGP WIQNKMEEIA RSSIQITGAL EDQMNQLKQY EHNIINYKNN
     IDKLEGDHQL IQEALVFDNK HTNYTMEHIR VGWELLLTTI ARTINEVETQ ILTRDAKGIT
     QEQMNEFRAS FNHFDRRKNG LMDHEDFRAC LISMGYDLGE AEFARIMTLV DPNGQGTVTF
     QSFIDFMTRE TADTDTAEQV IASFRILASD KPYILAEELR RELPPDQAQY CIKRMPAYSG
     PGSVPGGLDY AAFSSALYGE SDL
//