UniProt: B7Z313

Database: UniProt
Entry: B7Z313_HUMAN

LinkDB:  B7Z313_HUMAN 
Original site:  B7Z313_HUMAN

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Ontology (44)   
   GO (44)   
Gene (1)   
   UniGene (1)   
Protein sequence (1)   
   IPI (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (11)   
   InterPro (5)   
   Pfam (3)   
   PROSITE (1)   
   PRINTS (2)   
All databases (58)   

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ID   B7Z313_HUMAN            Unreviewed;       278 AA.
AC   B7Z313;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   29-MAY-2013, entry version 30.
DE   SubName: Full=cDNA FLJ50525, highly similar to Amyloid beta A4 protein (APP) (ABPP) (Alzheimer disease amyloid protein homolog);
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Corpus callosum;
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA   Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA   Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA   Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AK295373; BAH12049.1; -; mRNA.
DR   IPI; IPI00394658; -.
DR   UniGene; Hs.434980; -.
DR   PRIDE; B7Z313; -.
DR   UCSC; uc011acg.2; human.
DR   HOGENOM; HOG000232190; -.
DR   HOVERGEN; HBG000051; -.
DR   OrthoDB; EOG45B1F4; -.
DR   NextBio; 35479126; -.
DR   ArrayExpress; B7Z313; -.
DR   Bgee; B7Z313; -.
DR   GO; GO:0045177; C:apical part of cell; IEA:Compara.
DR   GO; GO:0030424; C:axon; IEA:Compara.
DR   GO; GO:0035253; C:ciliary rootlet; IEA:Compara.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IEA:Compara.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:Compara.
DR   GO; GO:0016021; C:integral to membrane; IEA:Compara.
DR   GO; GO:0031594; C:neuromuscular junction; IEA:Compara.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
DR   GO; GO:0005886; C:plasma membrane; IEA:Compara.
DR   GO; GO:0051233; C:spindle midzone; IEA:Compara.
DR   GO; GO:0003677; F:DNA binding; IEA:Compara.
DR   GO; GO:0016504; F:peptidase activator activity; IEA:Compara.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Compara.
DR   GO; GO:0008088; P:axon cargo transport; IEA:Compara.
DR   GO; GO:0016199; P:axon midline choice point recognition; IEA:Compara.
DR   GO; GO:0006878; P:cellular copper ion homeostasis; IEA:Compara.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Compara.
DR   GO; GO:0048669; P:collateral sprouting in absence of injury; IEA:Compara.
DR   GO; GO:0016358; P:dendrite development; IEA:Compara.
DR   GO; GO:0006897; P:endocytosis; IEA:Compara.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Compara.
DR   GO; GO:0030900; P:forebrain development; IEA:Compara.
DR   GO; GO:0000085; P:G2 phase of mitotic cell cycle; IEA:Compara.
DR   GO; GO:0006917; P:induction of apoptosis; IEA:Compara.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IEA:Compara.
DR   GO; GO:0007617; P:mating behavior; IEA:Compara.
DR   GO; GO:0006378; P:mRNA polyadenylation; IEA:Compara.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Compara.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Compara.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Compara.
DR   GO; GO:0016322; P:neuron remodeling; IEA:Compara.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IEA:Compara.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Compara.
DR   GO; GO:0007176; P:regulation of epidermal growth factor-activated receptor activity; IEA:Compara.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Compara.
DR   GO; GO:0043393; P:regulation of protein binding; IEA:Compara.
DR   GO; GO:0050803; P:regulation of synapse structure and activity; IEA:Compara.
DR   GO; GO:0006417; P:regulation of translation; IEA:Compara.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Compara.
DR   GO; GO:0051563; P:smooth endoplasmic reticulum calcium ion homeostasis; IEA:Compara.
DR   GO; GO:0001967; P:suckling behavior; IEA:Compara.
DR   GO; GO:0051124; P:synaptic growth at neuromuscular junction; IEA:Compara.
DR   GO; GO:0008542; P:visual learning; IEA:Compara.
DR   Gene3D; 4.10.230.10; -; 1.
DR   InterPro; IPR008155; Amyloid_glyco.
DR   InterPro; IPR013803; Amyloid_glyco_Abeta.
DR   InterPro; IPR024329; Amyloid_glyco_E2_domain.
DR   InterPro; IPR019745; Amyloid_glyco_intracell_CS.
DR   InterPro; IPR019543; APP_amyloid_C.
DR   Pfam; PF10515; APP_amyloid; 1.
DR   Pfam; PF12925; APP_E2; 1.
DR   Pfam; PF03494; Beta-APP; 1.
DR   PRINTS; PR00203; AMYLOIDA4.
DR   PRINTS; PR00204; BETAAMYLOID.
DR   SUPFAM; SSF109843; SSF109843; 1.
DR   PROSITE; PS00320; A4_INTRA; 1.
PE   2: Evidence at transcript level;
SQ   SEQUENCE   278 AA;  31450 MW;  0E42419A05F5387E CRC64;
     MLKKYVRAEQ KDRQHTLKHF EHVRMVDPKK AAQIRSQVMT HLRVIYERMN QSLSLLYNVP
     AVAEEIQDEV DELLQKEQNY SDDVLANMIS EPRISYGNDA LMPSLTETKT TVELLPVNGE
     FSLDDLQPWH SFGADSVPAN TENEVEPVDA RPAADRGLTT RPGSGLTNIK TEEISEVKMD
     AEFRHDSGYE VHHQKLVFFA EDVGSNKGAI IGLMVGGVVI ATVIVITLVM LKKKQYTSIH
     HGVVEVDAAV TPEERHLSKM QQNGYENPTY KFFEQMQN
//

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