ID B7Z3M7_HUMAN Unreviewed; 152 AA.
AC B7Z3M7;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=cDNA FLJ59908, highly similar to Tumor necrosis factor receptor superfamily member 10B {ECO:0000313|EMBL:BAH12263.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAH12263.1};
RN [1] {ECO:0000313|EMBL:BAH12263.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Thalamus {ECO:0000313|EMBL:BAH12263.1};
RA Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A.,
RA Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y.,
RA Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.,
RA Sugano S., Nomura N., Isogai T.;
RT "NEDO human cDNA sequencing project focused on splicing variants.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AK296128; BAH12263.1; -; mRNA.
DR AlphaFoldDB; B7Z3M7; -.
DR PeptideAtlas; B7Z3M7; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd08315; Death_TRAILR_DR4_DR5; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR034029; TNFRSF10A/B_death.
DR PANTHER; PTHR46330; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B; 1.
DR PANTHER; PTHR46330:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B; 1.
DR Pfam; PF00531; Death; 1.
DR SMART; SM00005; DEATH; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:BAH12263.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 65..134
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 152 AA; 17025 MW; 4A3A3B4DAF06867F CRC64;
MEVQEPAEPT GVNMLSPGES EHLLEPAEAE RSQRRRLLVP ANEGDPTETL RQCFDDFADL
VPFDSWEPLM RKLGLMDNEI KVAKAEAAGH RDTLYTMLIK WVNKTGRDAS VHTLLDALET
LGERLAKQKI EDHLLSSGKF MYLEGNADSA MS
//
