ID B7Z8M7_HUMAN Unreviewed; 173 AA.
AC B7Z8M7;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Ras-related protein Rab-1A {ECO:0000256|ARBA:ARBA00039502};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAH14013.1};
RN [1] {ECO:0000313|EMBL:BAH14013.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Kidney {ECO:0000313|EMBL:BAH14013.1};
RA Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A.,
RA Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y.,
RA Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.,
RA Sugano S., Nomura N., Isogai T.;
RT "NEDO human cDNA sequencing project focused on splicing variants.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AK303678; BAH14013.1; -; mRNA.
DR RefSeq; XP_005264525.1; XM_005264468.1.
DR AlphaFoldDB; B7Z8M7; -.
DR SMR; B7Z8M7; -.
DR MaxQB; B7Z8M7; -.
DR PeptideAtlas; B7Z8M7; -.
DR ProteomicsDB; 6964; -.
DR DNASU; 5861; -.
DR GeneID; 5861; -.
DR CTD; 5861; -.
DR OrthoDB; 8685at2759; -.
DR BioGRID-ORCS; 5861; 148 hits in 1187 CRISPR screens.
DR GenomeRNAi; 5861; -.
DR GO; GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001806; Small_GTPase.
DR PANTHER; PTHR47977:SF26; LD21953P; 1.
DR PANTHER; PTHR47977; RAS-RELATED PROTEIN RAB; 1.
DR Pfam; PF00071; Ras; 2.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
PE 2: Evidence at transcript level;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT REGION 146..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..173
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 173 AA; 18990 MW; BE42EEBBD90985D2 CRC64;
MSSMNPEYDY LFKLLLIGDS GVGKSCLLLR FADDTYTESY ISTIGVDFKI RTIELDGKTI
KLQIESFNNV KQWLQEIDRY ASENVNKLLV GNKCDLTTKK VVDYTTAKEF ADSLGIPFLE
TSAKNATNVE QSFMTMAAEI KKRMGPGATA GGAEKSNVKI QSTPVKQSGG GCC
//
