ID   B7Z9F3_HUMAN            Unreviewed;       253 AA.
AC   B7Z9F3;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   24-JAN-2024, entry version 60.
DE   SubName: Full=cDNA, FLJ78817, highly similar to Metaxin-2 {ECO:0000313|EMBL:BAH14289.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAH14289.1};
RN   [1] {ECO:0000313|EMBL:BAH14289.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Cerebellum {ECO:0000313|EMBL:BAH14289.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A.,
RA   Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y.,
RA   Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.,
RA   Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project.";
RL   Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC       Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004294}.
CC   -!- SIMILARITY: Belongs to the metaxin family.
CC       {ECO:0000256|ARBA:ARBA00009170}.
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DR   EMBL; AK315918; BAH14289.1; -; mRNA.
DR   AlphaFoldDB; B7Z9F3; -.
DR   PeptideAtlas; B7Z9F3; -.
DR   GO; GO:0001401; C:SAM complex; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd03211; GST_C_Metaxin2; 1.
DR   CDD; cd03079; GST_N_Metaxin2; 1.
DR   Gene3D; 1.20.1050.10; -; 1.
DR   InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR   InterPro; IPR040079; Glutathione_S-Trfase.
DR   InterPro; IPR033468; Metaxin_GST.
DR   InterPro; IPR019564; Sam37/metaxin_N.
DR   PANTHER; PTHR12289; METAXIN RELATED; 1.
DR   PANTHER; PTHR12289:SF38; METAXIN-2; 1.
DR   Pfam; PF17171; GST_C_6; 1.
DR   Pfam; PF10568; Tom37; 1.
DR   SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR   SFLD; SFLDG01180; SUF1; 1.
DR   SUPFAM; SSF47616; GST C-terminal domain-like; 1.
PE   2: Evidence at transcript level;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          31..151
FT                   /note="Mitochondrial outer membrane transport complex
FT                   Sam37/metaxin N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10568"
FT   DOMAIN          177..239
FT                   /note="Metaxin glutathione S-transferase"
FT                   /evidence="ECO:0000259|Pfam:PF17171"
SQ   SEQUENCE   253 AA;  28824 MW;  6D688B8101AF70EA CRC64;
     MYIAAEPWPE NATLYQQLKG EQILLSDDAA SLAVQAFLQM CNLPIKVVCR ANAEYMSPSG
     KVPFIHVGNQ VVSELGPIVQ FVKAKGHSLS DGLEEVQKAE MKAYMELVNN MLLTAELYLQ
     WCDEATVGEI THARYGSPYP WPLNHILAYQ KQWEVKRKMK AIGWGKKTLD QVLEDVDQCC
     QALSQRLGTQ PYFFNKQPTE LDALVFGHLY TILTTQLTND ELSEKVKNYS NLLAFCRRIE
     QHYFEDRGKG RLS
//