ID B7ZM30_HUMAN Unreviewed; 1178 AA.
AC B7ZM30;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=CAMTA2 protein {ECO:0000313|EMBL:AAI44233.1};
GN Name=CAMTA2 {ECO:0000313|EMBL:AAI44233.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|EMBL:AAI44233.1};
RN [1] {ECO:0000313|EMBL:AAI44233.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBUNIT: May interact with calmodulin. {ECO:0000256|ARBA:ARBA00029480}.
CC -!- SIMILARITY: Belongs to the CAMTA family.
CC {ECO:0000256|ARBA:ARBA00008267}.
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DR EMBL; BC144232; AAI44233.1; -; mRNA.
DR RefSeq; XP_006721544.1; XM_006721481.3.
DR AlphaFoldDB; B7ZM30; -.
DR PeptideAtlas; B7ZM30; -.
DR DNASU; 23125; -.
DR OrthoDB; 470813at2759; -.
DR BioGRID-ORCS; 23125; 13 hits in 1180 CRISPR screens.
DR ChiTaRS; CAMTA2; human.
DR GenomeRNAi; 23125; -.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR GO; GO:0051171; P:regulation of nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0080090; P:regulation of primary metabolic process; IEA:UniProt.
DR Gene3D; 1.20.5.190; -; 2.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005559; CG-1_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR PANTHER; PTHR23335:SF9; CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 2; 1.
DR PANTHER; PTHR23335; CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA; 1.
DR Pfam; PF03859; CG-1; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM01076; CG-1; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS51437; CG_1; 1.
DR PROSITE; PS50096; IQ; 1.
PE 2: Evidence at transcript level;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT DOMAIN 30..156
FT /note="CG-1"
FT /evidence="ECO:0000259|PROSITE:PS51437"
FT REGION 239..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 337..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 397..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..850
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 882..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..261
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..279
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..453
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..836
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1178 AA; 128602 MW; 28A4C2ED043ECE79 CRC64;
MNTKDTTEVA ENSHHLKIFL PKKLLECLPR CPLLPPERLR WNTNEEIASY LITFEKHDEW
LSCAPKTRPQ NGSIILYNRK KVKYRKDGYL WKKRKDGKTT REDHMKLKVQ GMENPDIVLV
HYLNVPALED CGKGCSPIFC SISSDRREWL KWSREELLGQ LKPMFHGIKW SCGNGTEEFS
VEHLVQQILD THPTKPAPRT HACLCSGGLG SGSLTHKCSS TKHRIISPKV EPRALTLTSI
PHAHPPEPPP LIAPLPPELP KAHTSPSSSS SSSSSGFAEP LEIRPSPPTS RGGSSRGGTA
ILLLTGLEQR AGGLTPTRHL APQADPRPSM SLAVVVGTEP SAPPAPPSPA FDPDRFLNSP
QRGQTYGGGQ GVSPDFPEAE AAHTPCSALE PAAALEPQAA ARGPPPQSVA GGRRGNCFFI
QDDDSGEELK GHGAAPPIPS PPPSPPPSPA PLEPSSRVGR GEALFGGPVG ASELEPFSLS
SFPDLMGELI SDEAPSIPAP TPQLSPALST ITDFSPEWSY PEGGVKVLIT GPWTEAAEHY
SCVFDHIAVP ASLVQPGVLR CYCPAHEVGL VSLQVAGREG PLSASVLFEY RARRFLSLPS
TQLDWLSLDD NQFRMSILER LEQMEKRMAE IAAAGQVPCQ GPDAPPVQDE GQGPGFEARV
VVLVESMIPR STWKGPERLA HGSPFRGMSL LHLAAAQGYA RLIETLSQWR SVETGSLDLE
QEVDPLNVDH FSCTPLMWAC ALGHLEAAVL LFRWNRQALS IPDSLGRLPL SVAHSRGHVR
LARCLEELQR QEPSVEPPFA LSPPSSSPDT GLSSVSSPSE LSDGTFSVTS AYSSAPDGSP
PPAPLPASEM TMEDMAPGQL SSGVPEAPLL LMDYEATNSK GPLSSLPALP PASDDGAAPE
DADSPQAVDV IPVDMISLAK QIIEATPERI KREDFVGLPE AGASMRERTG AVGLSETMSW
LASYLENVDH FPSSTPPSEL PFERGRLAVP SAPSWAEFLS ASTSGKMESD FALLTLSDHE
QRELYEAARV IQTAFRKYKG RRLKEQQEVA AAVIQRCYRK YKQLTWIALK FALYKKMTQA
AILIQSKFRS YYEQKRFQQS RRAAVLIQQH YRSYRRRPGP PHRTSATLPA RNKGSFLTKK
QDQAARKIMR FLRRCRHRMR ELKQNQELEG LPQPGLAT
//
