ID B8C257_THAPS Unreviewed; 649 AA.
AC B8C257;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE RecName: Full=WW domain-containing protein {ECO:0000259|PROSITE:PS50020};
GN ORFNames=THAPSDRAFT_22623 {ECO:0000313|EMBL:EED92331.1};
OS Thalassiosira pseudonana (Marine diatom) (Cyclotella nana).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=35128 {ECO:0000313|EMBL:EED92331.1, ECO:0000313|Proteomes:UP000001449};
RN [1] {ECO:0000313|EMBL:EED92331.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED92331.1};
RX PubMed=15459382; DOI=10.1126/science.1101156;
RA Armbrust E.V., Berges J.A., Bowler C., Green B.R., Martinez D.,
RA Putnam N.H., Zhou S., Allen A.E., Apt K.E., Bechner M., Brzezinski M.A.,
RA Chaal B.K., Chiovitti A., Davis A.K., Demarest M.S., Detter J.C.,
RA Glavina T., Goodstein D., Hadi M.Z., Hellsten U., Hildebrand M.,
RA Jenkins B.D., Jurka J., Kapitonov V.V., Kroger N., Lau W.W., Lane T.W.,
RA Larimer F.W., Lippmeier J.C., Lucas S., Medina M., Montsant A., Obornik M.,
RA Parker M.S., Palenik B., Pazour G.J., Richardson P.M., Rynearson T.A.,
RA Saito M.A., Schwartz D.C., Thamatrakoln K., Valentin K., Vardi A.,
RA Wilkerson F.P., Rokhsar D.S.;
RT "The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and
RT metabolism.";
RL Science 306:79-86(2004).
RN [2] {ECO:0000313|EMBL:EED92331.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED92331.1};
RX PubMed=18923393; DOI=10.1038/nature07410;
RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A.,
RA Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.,
RA Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P.,
RA Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C.,
RA Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D.,
RA Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G.,
RA La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J.,
RA Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A.,
RA Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L.,
RA Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A.,
RA Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R.,
RA Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S.,
RA Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA Grigoriev I.V.;
RT "The Phaeodactylum genome reveals the evolutionary history of diatom
RT genomes.";
RL Nature 456:239-244(2008).
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DR EMBL; CM000642; EED92331.1; -; Genomic_DNA.
DR RefSeq; XP_002290579.1; XM_002290543.1.
DR AlphaFoldDB; B8C257; -.
DR STRING; 35128.B8C257; -.
DR PaxDb; 35128-Thaps22623; -.
DR EnsemblProtists; EED92331; EED92331; THAPSDRAFT_22623.
DR GeneID; 7451766; -.
DR KEGG; tps:THAPSDRAFT_22623; -.
DR eggNOG; KOG1676; Eukaryota.
DR HOGENOM; CLU_422454_0_0_1; -.
DR InParanoid; B8C257; -.
DR OMA; PEMEGVQ; -.
DR Proteomes; UP000001449; Chromosome 5.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR CDD; cd00105; KH-I; 3.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 3.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR PANTHER; PTHR10288:SF171; P-ELEMENT SOMATIC INHIBITOR, ISOFORM C; 1.
DR Pfam; PF00013; KH_1; 3.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00322; KH; 3.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 3.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS50084; KH_TYPE_1; 3.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001449};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 615..648
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 95..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 649 AA; 68026 MW; 99E79910BBF2061B CRC64;
MAATRKRKST RTPAKSKKAK AAEEEAEEAA VPDETTVDDT AADGAAAATT TTDGGEEEDD
DVPPTPMINV DSKEQDAAAA LTALMGGTPK KVLVETNSTE IKGDVNENSG NGVDPAAEHT
KKEDSAPLKQ EAVAAEGNPN APGEETPTVM HSAVKSENPT QTTSNPGSNP GNTNPEVVAN
PPTTQPTAAP PIAAAPQVVM APAPSAVPSG VPTLATPAAP VVAAVSAPVE QEFEETGQVS
MLYVGRVIGK GGEMIRDLQA RSGCRIDVDQ NVPEGAPRII TYRGTRNAID FAKQLISILC
TEHGKEAELP LGQAMKKLVL VPSTVIGKII GRGGEMIREL QSKSMAKIQV DHSGAGMDSQ
QRQITVTGTT QAVIKAEEMI LFLAANPAVD AQESLALLIR DKTMNGGVWG SGPPYVNLPN
QGQGMADTGG GMYGGGAYGA VQPAAAAYGA YGAQQPAVAA YGGVGGIEHE LYPCSKMYMG
RVIGQKGVTI NDLQKRSGCD IQINQNVPVG MDCEINIKGS RQGIEMAKQM IQEIIELGPN
HSYAGGRGGG DQYGQHGGYQ QQAYQQGGYG NQAYPAQSYP PQQQYGMQQQ PYGGLQMYQQ
QTYGQPQMYG APMPPALTSP WRSATAADGQ VYYYNQNTGE TQWDKPPGL
//
