ID B8CFI7_THAPS Unreviewed; 2113 AA.
AC B8CFI7;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 79.
DE RecName: Full=BEACH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=THAPSDRAFT_25722 {ECO:0000313|EMBL:EED87633.1};
OS Thalassiosira pseudonana (Marine diatom) (Cyclotella nana).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=35128 {ECO:0000313|EMBL:EED87633.1, ECO:0000313|Proteomes:UP000001449};
RN [1] {ECO:0000313|EMBL:EED87633.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED87633.1};
RX PubMed=15459382; DOI=10.1126/science.1101156;
RA Armbrust E.V., Berges J.A., Bowler C., Green B.R., Martinez D.,
RA Putnam N.H., Zhou S., Allen A.E., Apt K.E., Bechner M., Brzezinski M.A.,
RA Chaal B.K., Chiovitti A., Davis A.K., Demarest M.S., Detter J.C.,
RA Glavina T., Goodstein D., Hadi M.Z., Hellsten U., Hildebrand M.,
RA Jenkins B.D., Jurka J., Kapitonov V.V., Kroger N., Lau W.W., Lane T.W.,
RA Larimer F.W., Lippmeier J.C., Lucas S., Medina M., Montsant A., Obornik M.,
RA Parker M.S., Palenik B., Pazour G.J., Richardson P.M., Rynearson T.A.,
RA Saito M.A., Schwartz D.C., Thamatrakoln K., Valentin K., Vardi A.,
RA Wilkerson F.P., Rokhsar D.S.;
RT "The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and
RT metabolism.";
RL Science 306:79-86(2004).
RN [2] {ECO:0000313|EMBL:EED87633.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED87633.1};
RX PubMed=18923393; DOI=10.1038/nature07410;
RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A.,
RA Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.,
RA Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P.,
RA Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C.,
RA Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D.,
RA Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G.,
RA La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J.,
RA Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A.,
RA Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L.,
RA Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A.,
RA Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R.,
RA Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S.,
RA Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA Grigoriev I.V.;
RT "The Phaeodactylum genome reveals the evolutionary history of diatom
RT genomes.";
RL Nature 456:239-244(2008).
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DR EMBL; CM000653; EED87633.1; -; Genomic_DNA.
DR RefSeq; XP_002294853.1; XM_002294817.1.
DR STRING; 35128.B8CFI7; -.
DR PaxDb; 35128-Thaps25722; -.
DR EnsemblProtists; EED87633; EED87633; THAPSDRAFT_25722.
DR GeneID; 7442830; -.
DR KEGG; tps:THAPSDRAFT_25722; -.
DR eggNOG; KOG1786; Eukaryota.
DR HOGENOM; CLU_232223_0_0_1; -.
DR InParanoid; B8CFI7; -.
DR Proteomes; UP000001449; Chromosome 22.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR46866; GH12955P; 1.
DR PANTHER; PTHR46866:SF1; GH12955P; 1.
DR Pfam; PF02138; Beach; 2.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001449};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 102..186
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 924..1045
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 78..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 710..734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 749..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1564..1598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1624..1655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..255
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 714..731
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..775
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1577..1598
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1639..1655
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2113 AA; 236115 MW; AF79B7B1A0DFF1A7 CRC64;
MNGCDVSVSS ASATDGRPTS TSPSPRTTQP SRQTITSLAI DILENSFKFY HAWAPTSLED
IDRDDSWQSF RSSTDAIANG QMKVDGVNSN DDGGRGNDES NNTIQVSGLS SDGTVDEDGL
RDFFSVFGHV TDAKIKPPTQ QHKQHQEGEN TAIVTFESGD GGIQKVLDAQ PIKMFGRVIY
VQLASTWEGN EVIVGESSDM QQQSPNKACN NTTTDSNRLP SPLVVAPPNY GSWYKGQQQN
QKSYLKPSSQ RASPYSARKV PMGKLSAAAS KMRMSNFNRP STTALDSQPL LTSSLPANFQ
MSAMSIIPQK DPAQSMGVDV SSSLHSLLTS SVEDPLFDDD DVHDEAGILT HKIRHGNATM
FDEMNSAGRI YHFHSDDALP SWVWAPAQRE LTNCSDAERD LSNTLELRRG VHAKLPLFSM
LSSVRGGLES TIDEQEEKEW LERTNLHLLH KAIAVTATDG SGDDAQKTGS YKLYQARHPC
LAPIISVTKC SASAPVNALD DNDHERLEAI VSVFDITPSQ HRPLHELLRT GEFLTKPLWQ
GIKGHDLEKL DVESVRDAKQ RESKFARFNT EDDGGDLCQC HKQFDRGRGG KVQQHHIEST
MRHELSSLSS AVLSSLTEHQ MFDELRRLHN HPQLYSRRGT QRRMLRVGAS NLANVVDLRI
RFLALQLFKA VSFCHSRGVV LGDQLRPDRV FIEDEMWIRL AVPVVNIEDN MQSSESESKS
KHRDDDCTRV DQQSLAVKSN NRRSIFHRYS NHSDASPNNK TSHHARASQS EETPSVVPYP
GFGLVPLEQW RRGYITNLYY LMMLNAAAGR TIGNQTNPPI LPWVTDFTAE IGRINDTEAD
CNAWRDMSKS KYRLNKGDEQ LDQTFLRGSP SHHVPETITD LTSTVRTAFI PQHYPDSIER
MYSWTPDEAT HEFYMTSSQP SIFKSRHEEM CDISLPRWCG GNEDTFIAYH RRLLESDHVS
LQLHHWIDLN FGDALVGERA VAEKNVVLHR VSWSGGSCME GKDQCIGDCH SVFSGNATDE
STEECQKSLN KSVFVQLFLS PHPEKIVHTN VSRIEAKPRS SDHTADFVLR KQHDISLIGA
ILKECYSSAK VIPPFSVDAA INDLLSGTHD VKRSLKGIAK GEATDKRFPF PPHLQDLYTF
MSNIQSASFK RGESDSLVNG HMGRSSDLER VWAIIRKNHN LEVLSDASIA LMLPTLLSPL
TCTHAFIENS LSSSGYASFP ERLCSYLIQM SRKVPAALVV PSLLRFLDHS SKLALGSLAI
TNALGKVYLS HDLLPRLYLR SSWEGFVKQL TTFMTSQLRR MSTTSETGSL ESKGQMRIKS
VVSFFVSFVA HDDVLGMSII CRYIIPSLVR IIDKCSSNDN ENQCVQVMKL MMPFQPEDVL
GVLICKPILR ILSQHLSSLL RPVIPTVLYV TDLVALLQFS LRHLDSNHIL QYFFQSNSGT
ISQLLLASFE ATTQGKELEK LNDLFRDVCL LLSDMILKVD PEHFRETLFP IIEALSSQMN
DRYLTISLRR SIGSKEFEWS EIMLLPGICN GCTLVGKIAS VCERETLRTC CPSALELLSW
AAKPEDSSPK GINPPVNRTE EVKRHSANTE ARSREEEGRI SFGRILKTST SSEKDIEMLA
PARDTSYDDL PPTIDDTNPY GVPQRQNKER SSTHSMQFVY DEQLSKQKRD LAWVMGLHRR
KMDDSISYSW QPRMMTTTKL DFAPSIGSDG SIDPRASITC MSTNASESML LAGNSIGEVL
LFDLRRQPPS LMHRQQVPFN THDGTVNPIS QADFFNREES VLVCDGGLHQ WDIETQKIRS
SLSRDNAYHN DNTRVQCPWQ GDRFVKFSVF PKLSGHGELI DASFGEIAAI TPNHLCTVDM
RCRRSVATYE QLVQSGIASS CCEQPPQFDS MFKQLIWNID GVGYSSEHLN SRKKTTPEAE
PLSSFKLNCI TTHCGEGDWI CVGSSSGHIH LFDRRRGKLV ICWKAHSLSI EYLQSVSRHR
LLSVSADKTA VVWDLSRNPP QKVSSICNLP GKENTMNISS HQFQAEDGLV SIPGGDFLLC
CVTGRKAVFQ PMSLHPNLSD EDNIDIKAER IVMSNWDGSS ISSSSKLNIS SVALLPCRQL
VLLGCDGEIH VCL
//
