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Database: UniProt
Entry: B8CU29
LinkDB: B8CU29
Original site: B8CU29 
ID   TRMN6_SHEPW             Reviewed;         241 AA.
AC   B8CU29;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 2.
DT   29-OCT-2014, entry version 38.
DE   RecName: Full=tRNA1(Val) (adenine(37)-N6)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_01872};
DE            EC=2.1.1.223 {ECO:0000255|HAMAP-Rule:MF_01872};
DE   AltName: Full=tRNA m6A37 methyltransferase {ECO:0000255|HAMAP-Rule:MF_01872};
GN   OrderedLocusNames=swp_4230;
OS   Shewanella piezotolerans (strain WP3 / JCM 13877).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=225849;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WP3 / JCM 13877;
RX   PubMed=18398463; DOI=10.1371/journal.pone.0001937;
RA   Wang F., Wang J., Jian H., Zhang B., Li S., Wang F., Zeng X., Gao L.,
RA   Bartlett D.H., Yu J., Hu S., Xiao X.;
RT   "Environmental adaptation: genomic analysis of the piezotolerant and
RT   psychrotolerant deep-sea iron reducing bacterium Shewanella
RT   piezotolerans WP3.";
RL   PLoS ONE 3:E1937-E1937(2008).
CC   -!- FUNCTION: Specifically methylates the adenine in position 37 of
CC       tRNA(1)(Val) (anticodon cmo5UAC). {ECO:0000255|HAMAP-
CC       Rule:MF_01872}.
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + adenine(37) in
CC       tRNA(1)(Val) = S-adenosyl-L-homocysteine + N(6)-methyladenine(37)
CC       in tRNA(1)(Val). {ECO:0000255|HAMAP-Rule:MF_01872}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01872}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. tRNA
CC       (adenine-N(6)-)-methyltransferase family. {ECO:0000255|HAMAP-
CC       Rule:MF_01872}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ACJ30885.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000472; ACJ30885.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; YP_002313472.1; NC_011566.1.
DR   ProteinModelPortal; B8CU29; -.
DR   STRING; 225849.swp_4230; -.
DR   EnsemblBacteria; ACJ30885; ACJ30885; swp_4230.
DR   GeneID; 7035170; -.
DR   KEGG; swp:swp_4230; -.
DR   PATRIC; 23546783; VBIShePie65056_3889.
DR   eggNOG; COG4123; -.
DR   HOGENOM; HOG000283147; -.
DR   KO; K15460; -.
DR   OrthoDB; EOG66TGB2; -.
DR   BioCyc; SPIE225849:GH6V-4107-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
DR   GO; GO:0016430; F:tRNA (adenine-N6-)-methyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.150; -; 1.
DR   HAMAP; MF_01872; tRNA_methyltr_YfiC; 1.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR002296; N12N6_MeTrfase.
DR   InterPro; IPR020596; rRNA_Ade_Mease_Trfase_CS.
DR   InterPro; IPR029063; SAM-dependent_MTases-like.
DR   InterPro; IPR022882; tRNA_adenine-N6_MeTrfase.
DR   PRINTS; PR00507; N12N6MTFRASE.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Methyltransferase;
KW   S-adenosyl-L-methionine; Transferase; tRNA processing.
FT   CHAIN         1    241       tRNA1(Val) (adenine(37)-N6)-
FT                                methyltransferase.
FT                                /FTId=PRO_0000387425.
SQ   SEQUENCE   241 AA;  26419 MW;  2E953F597FFFFEF8 CRC64;
     MPFSFKQFHI DDRRCGMPVS TDGVLLGAWA PLSNSKNILD IGAGSGLLSL MAAQRSKANI
     TAIELDENAA LDCQSNFNLS PWSKRLTLLT RSIQQFCTTA KKHSFDHIIC NPPYFDNGPQ
     SNSALRATAR HTDSLSFDEL LTAISSLLSP AGQASLILPI TGANQLLQQL EQHQLTCQHA
     VLVASVEGKK PNRQLLLITP CRSNFANQAT THPVSNLVIR NTDGHYSDDF ILLSKSFYLK
     L
//
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