ID B8CY31_HALOH Unreviewed; 333 AA.
AC B8CY31;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:ACL70200.1};
DE EC=5.1.1.1 {ECO:0000313|EMBL:ACL70200.1};
GN OrderedLocusNames=Hore_14510 {ECO:0000313|EMBL:ACL70200.1};
OS Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562).
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Halothermotrichaceae;
OC Halothermothrix.
OX NCBI_TaxID=373903 {ECO:0000313|EMBL:ACL70200.1, ECO:0000313|Proteomes:UP000000719};
RN [1] {ECO:0000313|EMBL:ACL70200.1, ECO:0000313|Proteomes:UP000000719}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H 168 / OCM 544 / DSM 9562 {ECO:0000313|Proteomes:UP000000719};
RX PubMed=19145256; DOI=10.1371/journal.pone.0004192;
RA Mavromatis K., Ivanova N., Anderson I., Lykidis A., Hooper S.D., Sun H.,
RA Kunin V., Lapidus A., Hugenholtz P., Patel B., Kyrpides N.C.;
RT "Genome analysis of the anaerobic thermohalophilic bacterium
RT Halothermothrix orenii.";
RL PLoS ONE 4:E4192-E4192(2009).
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DR EMBL; CP001098; ACL70200.1; -; Genomic_DNA.
DR RefSeq; WP_012636383.1; NC_011899.1.
DR AlphaFoldDB; B8CY31; -.
DR STRING; 373903.Hore_14510; -.
DR KEGG; hor:Hore_14510; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_0_9; -.
DR OrthoDB; 9784962at2; -.
DR Proteomes; UP000000719; Chromosome.
DR GO; GO:0008784; F:alanine racemase activity; IEA:UniProtKB-EC.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000313|EMBL:ACL70200.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000719};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..58
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 333 AA; 37216 MW; B36B174626198A8E CRC64;
MDKITMKDIA KAAKVSKSTV SRALSNDPRV NEETRKKVVK IAREMNYRPH QVAQALAKKN
TNIIGVVLPT FPRTVADPFF LEFLQGIGEI AVEKGYSLTL PNLARKEIQN LGQVINKNTV
DGVILTEPKI DDPRIKYLKE KEIPFVFLGN PMDKDDVYWV ETDNIRGSYL AMEYLIKSGH
KKIATVAGSP DLVAGKYRYL GYKKALENYG LTIDKNLVCY ADFTEEGAYS AVLKLLEKRN
DFTAIFVAND LMAFGVIKAL KEKGLSIPED IAVMGYDGIK LGEFIEPPLS TIKIPSRQMG
RVALNLLIKL INGENVKDKH VLLPPELMVR ESA
//
