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Database: UniProt
Entry: B8DQA5_DESVM
LinkDB: B8DQA5_DESVM
Original site: B8DQA5_DESVM 
ID   B8DQA5_DESVM            Unreviewed;       444 AA.
AC   B8DQA5;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   05-JUL-2017, entry version 71.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN   OrderedLocusNames=DvMF_2081 {ECO:0000313|EMBL:ACL09024.1};
OS   Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfovibrionaceae; Desulfovibrio.
OX   NCBI_TaxID=883 {ECO:0000313|EMBL:ACL09024.1, ECO:0000313|Proteomes:UP000001361};
RN   [1] {ECO:0000313|Proteomes:UP000001361}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Miyazaki F / DSM 19637 {ECO:0000313|Proteomes:UP000001361};
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Hazen T.C., Richardson P.;
RT   "Complete sequence of Desulfovibrio vulgaris str. 'Miyazaki F'.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577,
CC       ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP001197; ACL09024.1; -; Genomic_DNA.
DR   RefSeq; WP_012613196.1; NC_011769.1.
DR   STRING; 883.DvMF_2081; -.
DR   EnsemblBacteria; ACL09024; ACL09024; DvMF_2081.
DR   KEGG; dvm:DvMF_2081; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000227577; -.
DR   KO; K02313; -.
DR   OMA; DFRYLQG; -.
DR   OrthoDB; POG091H02FF; -.
DR   BioCyc; DVUL883:GCJ5-2114-MONOMER; -.
DR   Proteomes; UP000001361; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001361};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001361}.
FT   DOMAIN      134    267       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      349    418       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   444 AA;  50452 MW;  73018CB04720B225 CRC64;
     MLKKALRQHL QQTCQEQDLR QWYDPLAITL STNDKRLEVQ FPHSFFAQWF SATAQVTFES
     RLREFLGDGY VLRYSSGNGG SPQAAPAPKT ARQLDYPFGA RFTFDTFLSN RKNQFPVASA
     KEVARDGRDP HDRVYNPFVV CGGNGNGKTH LLRAIANELS RSRDENAIFC GPVDELGTRF
     EGLSATGAGA AQERQQARSR LCAHEVLVVD DLQRLRDQPF LQDELTFAFD HFHDHGKQMV
     FACSGKLADL DFLSPKLRSR LEWGLIVELR EPDLDVRLKF IQQQSRSRNI QLSKEHSLTL
     AQRFREFRHL QGILVKVGAY RQLVNRDIQD RELEQILRHT DSGKGNSLTP DAVIAATAEQ
     FGIPARDIIG DKRQQHIVQA RQVAMFLCRE LLGSSFPALG RVFGGKDHST AMYAVRKIKQ
     LQQSDKDMQL LVTDLKRKCL TRAE
//
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