ID   B8EJR7_METSB            Unreviewed;       343 AA.
AC   B8EJR7;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   SubName: Full=Pyridoxal-5'-phosphate-dependent protein beta subunit {ECO:0000313|EMBL:ACK49471.1};
GN   OrderedLocusNames=Msil_0499 {ECO:0000313|EMBL:ACK49471.1};
OS   Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB
OS   13906 / BL2).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Beijerinckiaceae; Methylocella.
OX   NCBI_TaxID=395965 {ECO:0000313|EMBL:ACK49471.1, ECO:0000313|Proteomes:UP000002257};
RN   [1] {ECO:0000313|EMBL:ACK49471.1, ECO:0000313|Proteomes:UP000002257}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2
RC   {ECO:0000313|Proteomes:UP000002257};
RX   PubMed=20472789; DOI=10.1128/JB.00506-10;
RA   Chen Y., Crombie A., Rahman M.T., Dedysh S.N., Liesack W., Stott M.B.,
RA   Alam M., Theisen A.R., Murrell J.C., Dunfield P.F.;
RT   "Complete genome sequence of the aerobic facultative methanotroph
RT   Methylocella silvestris BL2.";
RL   J. Bacteriol. 192:3840-3841(2010).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001280; ACK49471.1; -; Genomic_DNA.
DR   RefSeq; WP_012589541.1; NC_011666.1.
DR   AlphaFoldDB; B8EJR7; -.
DR   STRING; 395965.Msil_0499; -.
DR   KEGG; msl:Msil_0499; -.
DR   eggNOG; COG0031; Bacteria.
DR   HOGENOM; CLU_021018_1_0_5; -.
DR   OrthoDB; 9805733at2; -.
DR   Proteomes; UP000002257; Chromosome.
DR   GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:UniProt.
DR   GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR   CDD; cd01561; CBS_like; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   InterPro; IPR001216; P-phosphate_BS.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR   PANTHER; PTHR10314:SF211; PALP DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF00291; PALP; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR   PROSITE; PS00901; CYS_SYNTHASE; 1.
PE   4: Predicted;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002257}.
FT   DOMAIN          9..306
FT                   /note="Tryptophan synthase beta chain-like PALP"
FT                   /evidence="ECO:0000259|Pfam:PF00291"
SQ   SEQUENCE   343 AA;  35951 MW;  EEC6EF2060E4E9A0 CRC64;
     MAFAKSVIEA IGNTPLIKLR RASEETQCLI LGKAEFQNPG GSVKDRAALA IVADAVARGA
     LKPGGVIVEG TAGNTGIGLA LVANALGYKT VIVIPETQSQ EKKDLLRLQG AELIEVPAVP
     YADPNNYVKL SGRLAERLAK ENPAGAIWAN QFDNVANRQG HFETTGPEIF AQTDGRVDGF
     VSAVGTGGTL AGVGMALKAK NPGVQIALAD PPGAALYSYY TTGELKSSGS SITEGIGQGR
     ITANLEGAPI DFAYQIGDEE SVRLVFDLAE NEGLLLGGSS GVNVAGAIRL ARELGPGHTI
     VTILCDSGSR YQSKLFNPEF LRSKNLPTPG WLERPLQIKP DFL
//