ID B8FRD4_DESHD Unreviewed; 362 AA.
AC B8FRD4;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Transposase, IS605 OrfB family {ECO:0000313|EMBL:ACL20049.1};
DE EC=2.1.1.37 {ECO:0000313|EMBL:ACL20049.1};
GN OrderedLocusNames=Dhaf_2012 {ECO:0000313|EMBL:ACL20049.1};
OS Desulfitobacterium hafniense (strain DSM 10664 / DCB-2).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfitobacterium.
OX NCBI_TaxID=272564 {ECO:0000313|EMBL:ACL20049.1, ECO:0000313|Proteomes:UP000007726};
RN [1] {ECO:0000313|EMBL:ACL20049.1, ECO:0000313|Proteomes:UP000007726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10664 / DCB-2 {ECO:0000313|Proteomes:UP000007726};
RX PubMed=22316246; DOI=10.1186/1471-2180-12-21;
RA Kim S.H., Harzman C., Davis J.K., Hutcheson R., Broderick J.B., Marsh T.L.,
RA Tiedje J.M.;
RT "Genome sequence of Desulfitobacterium hafniense DCB-2, a Gram-positive
RT anaerobe capable of dehalogenation and metal reduction.";
RL BMC Microbiol. 12:21-21(2012).
CC -!- SIMILARITY: In the C-terminal section; belongs to the transposase 35
CC family. {ECO:0000256|ARBA:ARBA00008761}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the transposase 2
CC family. {ECO:0000256|ARBA:ARBA00011044}.
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DR EMBL; CP001336; ACL20049.1; -; Genomic_DNA.
DR AlphaFoldDB; B8FRD4; -.
DR KEGG; dhd:Dhaf_2012; -.
DR HOGENOM; CLU_032903_0_1_9; -.
DR Proteomes; UP000007726; Chromosome.
DR GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR InterPro; IPR010095; Cas12f1-like_TNB.
DR InterPro; IPR001959; Transposase.
DR InterPro; IPR021027; Transposase_put_HTH.
DR NCBIfam; NF040570; guided_TnpB; 1.
DR NCBIfam; TIGR01766; IS200/IS605 family accessory protein TnpB-like domain; 1.
DR PANTHER; PTHR30405:SF20; RNA-GUIDED DNA ENDONUCLEASE INSQ-RELATED; 1.
DR PANTHER; PTHR30405; TRANSPOSASE; 1.
DR Pfam; PF12323; HTH_OrfB_IS605; 1.
DR Pfam; PF01385; OrfB_IS605; 1.
DR Pfam; PF07282; OrfB_Zn_ribbon; 1.
PE 3: Inferred from homology;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:ACL20049.1};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Transferase {ECO:0000313|EMBL:ACL20049.1};
KW Transposition {ECO:0000256|ARBA:ARBA00022578};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 1..45
FT /note="Transposase putative helix-turn-helix"
FT /evidence="ECO:0000259|Pfam:PF12323"
FT DOMAIN 166..277
FT /note="Probable transposase IS891/IS1136/IS1341"
FT /evidence="ECO:0000259|Pfam:PF01385"
FT DOMAIN 289..355
FT /note="Cas12f1-like TNB"
FT /evidence="ECO:0000259|Pfam:PF07282"
SQ SEQUENCE 362 AA; 41960 MW; 61C83B5FBFFCB51C CRC64;
MQMVYRYEVY PSREQEQKLF HTLKLCRKLY NHALNERQVT YKETGHGLTY NQQQNALPAF
VKAHPEYSQV HSQVLQDVLR RLDSAYQHFF AKEAGYPRFK NRDHYSSLTY PQVDNVKRTF
GRAGYIYLSK LGFVKMETHR KFPVEAIKRV NIKYHGGKWF ANLTAEIPDV APVENPSQAV
GIDVGLNHFA VLSDEKVIDN PKYYRKMEKK LAKAQRRLSR KRKGSHNRGK AKVKVAKIHA
KIANQRKDFL HQASVRVVRS YDLIVMEDLK VHNMVRNRRL AKSIHDAGWG QFRNYIRYKC
ERQGKQFILV DPKGTSQSCL CGESVPKDLS VRVHECPSCG LVMDRDLVSS KLILARGLSK
IA
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