ID   B8G299_DESHD            Unreviewed;       744 AA.
AC   B8G299;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 93.
DE   SubName: Full=Sigma54 specific transcriptional regulator, Fis family {ECO:0000313|EMBL:ACL19417.1};
GN   OrderedLocusNames=Dhaf_1361 {ECO:0000313|EMBL:ACL19417.1};
OS   Desulfitobacterium hafniense (strain DSM 10664 / DCB-2).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC   Desulfitobacterium.
OX   NCBI_TaxID=272564 {ECO:0000313|EMBL:ACL19417.1, ECO:0000313|Proteomes:UP000007726};
RN   [1] {ECO:0000313|EMBL:ACL19417.1, ECO:0000313|Proteomes:UP000007726}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10664 / DCB-2 {ECO:0000313|Proteomes:UP000007726};
RX   PubMed=22316246; DOI=10.1186/1471-2180-12-21;
RA   Kim S.H., Harzman C., Davis J.K., Hutcheson R., Broderick J.B., Marsh T.L.,
RA   Tiedje J.M.;
RT   "Genome sequence of Desulfitobacterium hafniense DCB-2, a Gram-positive
RT   anaerobe capable of dehalogenation and metal reduction.";
RL   BMC Microbiol. 12:21-21(2012).
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DR   EMBL; CP001336; ACL19417.1; -; Genomic_DNA.
DR   RefSeq; WP_015943382.1; NC_011830.1.
DR   AlphaFoldDB; B8G299; -.
DR   KEGG; dhd:Dhaf_1361; -.
DR   HOGENOM; CLU_000445_8_4_9; -.
DR   Proteomes; UP000007726; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00009; AAA; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR002078; Sigma_54_int.
DR   InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR   InterPro; IPR025944; Sigma_54_int_dom_CS.
DR   PANTHER; PTHR32071:SF57; SIGMA L-DEPENDENT TRANSCRIPTIONAL REGULATOR YQIR-RELATED; 1.
DR   PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF02954; HTH_8; 1.
DR   Pfam; PF00158; Sigma54_activat; 1.
DR   PRINTS; PR01590; HTHFIS.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00065; GAF; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR   PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR   PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          448..678
FT                   /note="Sigma-54 factor interaction"
FT                   /evidence="ECO:0000259|PROSITE:PS50045"
FT   REGION          413..442
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   744 AA;  83102 MW;  F2C37067F5EB0475 CRC64;
     MRDELFESFP FGIIRIDSTN KIQRMNHYAK QLTHALDPES LETLLTLKPK NDITTWSVAN
     HQIALNVELF MVSGDSNRLL LLGLEPNFTS ALPPQFERAL EDLTTDPEEI VLRIVTMISE
     ATSFERFDLV RVNPQLRKYS YAYSIGLEIE GSIYAPYSQI RKTGLGWILE TEAPQLSSSL
     QPEGFSFSED PMLYRTGFRS ALRVPILFGH EVIGAILLGG TKALQFEIED AYLISQISRH
     FSQAFYHSGI IQERSYQAMA TSAFLHSMAE NLKDDHILDF LNDYCIQLQI ATQLESIYLC
     LLDQTHQQQK LLVSAGRKFP QKNEWKPLDK EIAAMLQAKS IVCYSLVHTS IQNTDELLNQ
     GFTSTLYAPI EHRETIVAAL VAAAMDEKAS SPYMSGLFKV ATEQLSSVVA RLPNAPGAVP
     EPNSSRQLPK PTRKDRLQDQ ETSGFSRIIG SSKIMQDTIQ NAARVAQYDF PILITGETGT
     GKELLAKAIH QSSQVAQGPF IVVNSAAIPA NLLESELFGY QEGAFSGGVK GGKPGKILLA
     NRGTLFLDEI GELSPELQAK LLRVIQEQEI EPLGAIKPIP IKVRILSATH RDLSSMVEQG
     EFREDLLYRL NSIEIKIPPL RERGQDILEL AEHMLQFLAQ SHDTPEKTLS PGAQDLFLKY
     TWPGNIRQLQ NIINRLYVFA EGSTIHTQDL PPDLRVAETD KGHSEKEEIA GLLAEFGGNK
     TALAQYLGIT RTGLWKKLKR LGLQ
//