ID B8GQA4_THISH Unreviewed; 103 AA.
AC B8GQA4;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Negative regulator of flagellin synthesis {ECO:0000256|ARBA:ARBA00017823};
DE AltName: Full=Anti-sigma-28 factor {ECO:0000256|ARBA:ARBA00030117};
GN OrderedLocusNames=Tgr7_1213 {ECO:0000313|EMBL:ACL72299.1};
OS Thioalkalivibrio sulfidiphilus (strain HL-EbGR7).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Thioalkalivibrio.
OX NCBI_TaxID=396588 {ECO:0000313|EMBL:ACL72299.1, ECO:0000313|Proteomes:UP000002383};
RN [1] {ECO:0000313|EMBL:ACL72299.1, ECO:0000313|Proteomes:UP000002383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HL-EbGR7 {ECO:0000313|EMBL:ACL72299.1,
RC ECO:0000313|Proteomes:UP000002383};
RX PubMed=21475584;
RA Muyzer G., Sorokin D.Y., Mavromatis K., Lapidus A., Clum A., Ivanova N.,
RA Pati A., d'Haeseleer P., Woyke T., Kyrpides N.C.;
RT "Complete genome sequence of 'Thioalkalivibrio sulfidophilus' HL-EbGr7.";
RL Stand. Genomic Sci. 4:23-35(2011).
CC -!- FUNCTION: Responsible for the coupling of flagellin expression to
CC flagellar assembly by preventing expression of the flagellin genes when
CC a component of the middle class of proteins is defective. It negatively
CC regulates flagellar genes by inhibiting the activity of FliA by
CC directly binding to FliA. {ECO:0000256|ARBA:ARBA00024739}.
CC -!- SIMILARITY: Belongs to the FlgM family.
CC {ECO:0000256|ARBA:ARBA00005322}.
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DR EMBL; CP001339; ACL72299.1; -; Genomic_DNA.
DR AlphaFoldDB; B8GQA4; -.
DR STRING; 396588.Tgr7_1213; -.
DR KEGG; tgr:Tgr7_1213; -.
DR eggNOG; COG2747; Bacteria.
DR HOGENOM; CLU_149304_0_4_6; -.
DR OrthoDB; 5738369at2; -.
DR Proteomes; UP000002383; Chromosome.
DR GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR035890; Anti-sigma-28_factor_FlgM_sf.
DR InterPro; IPR007412; FlgM.
DR InterPro; IPR031316; FlgM_C.
DR NCBIfam; TIGR03824; FlgM_jcvi; 1.
DR Pfam; PF04316; FlgM; 1.
DR SUPFAM; SSF101498; Anti-sigma factor FlgM; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|ARBA:ARBA00022795};
KW Reference proteome {ECO:0000313|Proteomes:UP000002383};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 44..98
FT /note="Anti-sigma-28 factor FlgM C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04316"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 103 AA; 10872 MW; D98D7DD86B4AAD22 CRC64;
MSIDIKNLSQ TQARATGDGR AVSDSRGSRG GEAGGSTSSR SSDDQVTLTD TARRLSDLTQ
TASAQPAVDS QRVAEIRQAI ADGSYQVNAE RVADKLMQTE DLL
//
