ID B8INC9_METNO Unreviewed; 306 AA.
AC B8INC9;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Dihydrodipicolinate synthetase {ECO:0000313|EMBL:ACL56455.1};
GN OrderedLocusNames=Mnod_1463 {ECO:0000313|EMBL:ACL56455.1};
OS Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylobacterium.
OX NCBI_TaxID=460265 {ECO:0000313|EMBL:ACL56455.1, ECO:0000313|Proteomes:UP000008207};
RN [1] {ECO:0000313|EMBL:ACL56455.1, ECO:0000313|Proteomes:UP000008207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 21967 / CNCM I-2342 / ORS 2060
RC {ECO:0000313|Proteomes:UP000008207};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Marx C.J.,
RA Richardson P.;
RT "Complete sequence of chromosome of Methylobacterium nodulans ORS 2060.";
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
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DR EMBL; CP001349; ACL56455.1; -; Genomic_DNA.
DR RefSeq; WP_015928151.1; NC_011894.1.
DR AlphaFoldDB; B8INC9; -.
DR STRING; 460265.Mnod_1463; -.
DR KEGG; mno:Mnod_1463; -.
DR eggNOG; COG0329; Bacteria.
DR HOGENOM; CLU_049343_5_1_5; -.
DR OrthoDB; 7157803at2; -.
DR Proteomes; UP000008207; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF67; BLR3884 PROTEIN; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000008207}.
FT ACT_SITE 142
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 172
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 50
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
FT BINDING 213
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 306 AA; 32322 MW; CD3D6558E381B6B7 CRC64;
MSETVFPRGV FCAALTPLDA DLNPNHAAFA AHCRHLLAEG CTGIALLGTT GEANSFSGDE
RRALLEAALQ AGISPDQLLP GTGVAALTET VALTRHALSL GVTTVVMLPP FYYKGVSEDG
IVAAYAEIVE RIGDERLRVV LYHIPQVAGV PLPHGAIARL RERYPGTFVG IKDSAGDLAH
MTALVERFPG FAVLAGADPL MLPLLKAGGA GAITATTNLV ARDLRFVFDH WADPAQAAAV
EAAQARVVAA RERASRFAQM ASLKALVAER TGDPGWRRMR PPLVPLSETE RAALLTPAPD
EARRAS
//
