ID B8ITK6_METNO Unreviewed; 373 AA.
AC B8ITK6;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:ACL58922.1};
GN OrderedLocusNames=Mnod_4043 {ECO:0000313|EMBL:ACL58922.1};
OS Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylobacterium.
OX NCBI_TaxID=460265 {ECO:0000313|EMBL:ACL58922.1, ECO:0000313|Proteomes:UP000008207};
RN [1] {ECO:0000313|EMBL:ACL58922.1, ECO:0000313|Proteomes:UP000008207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 21967 / CNCM I-2342 / ORS 2060
RC {ECO:0000313|Proteomes:UP000008207};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Marx C.J.,
RA Richardson P.;
RT "Complete sequence of chromosome of Methylobacterium nodulans ORS 2060.";
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC {ECO:0000256|ARBA:ARBA00007639}.
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DR EMBL; CP001349; ACL58922.1; -; Genomic_DNA.
DR RefSeq; WP_015930571.1; NC_011894.1.
DR AlphaFoldDB; B8ITK6; -.
DR STRING; 460265.Mnod_4043; -.
DR KEGG; mno:Mnod_4043; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_0_0_5; -.
DR OrthoDB; 9805774at2; -.
DR Proteomes; UP000008207; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06307; PBP1_sugar_binding; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR025997; SBP_2_dom.
DR PANTHER; PTHR46847; D-ALLOSE-BINDING PERIPLASMIC PROTEIN-RELATED; 1.
DR PANTHER; PTHR46847:SF1; D-ALLOSE-BINDING PERIPLASMIC PROTEIN-RELATED; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13407; Peripla_BP_4; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008207}.
FT DOMAIN 4..68
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 373 AA; 41149 MW; B6303BBD6A69C61D CRC64;
MPRPTIADVA KAANVSVSTV DRVLSGRHSV REATAERVQR AAEAVGFHLA GTIRHRLGQD
RPARTLGFLL QQRQNEFYET LGQVLQEATD ASTTIRGQAV VRFRDYQEEE VAAECLLQLG
RECNAVAVVA ADHPKVTQAI DTLHEEGVPV FALISELTAA NSAGYVGLDN WQVGGTAAWF
LSNMCRTPGK IGICVGSLCF QRASEMRFRS YFRERAPEFQ LLDSTVTLDD ERYAYECTRD
LLRQTPDLVG IYVAGGSITG VIRALRELPS AASRNLVVIG RELIPDTMRG LIEGLINVVL
SHPKKLLAET LVEAMAQSTI SNQGGSYVHP PIPFDIYAPE NLWAFRLSDL RGMYEPGWPW
RPNIARSRKL SGV
//
