ID B8M0D7_TALSN Unreviewed; 584 AA.
AC B8M0D7;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Bicyclomycin resistance protein, putative {ECO:0000313|EMBL:EED21234.1};
GN ORFNames=TSTA_084650 {ECO:0000313|EMBL:EED21234.1};
OS Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS 1006) (Penicillium stipitatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441959 {ECO:0000313|EMBL:EED21234.1, ECO:0000313|Proteomes:UP000001745};
RN [1] {ECO:0000313|Proteomes:UP000001745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC {ECO:0000313|Proteomes:UP000001745};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; EQ962653; EED21234.1; -; Genomic_DNA.
DR RefSeq; XP_002478197.1; XM_002478152.1.
DR AlphaFoldDB; B8M0D7; -.
DR STRING; 441959.B8M0D7; -.
DR GeneID; 8102933; -.
DR VEuPathDB; FungiDB:TSTA_084650; -.
DR eggNOG; KOG0255; Eukaryota.
DR HOGENOM; CLU_008455_11_2_1; -.
DR InParanoid; B8M0D7; -.
DR OMA; ILPISMY; -.
DR OrthoDB; 1701554at2759; -.
DR PhylomeDB; B8M0D7; -.
DR Proteomes; UP000001745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17323; MFS_Tpo1_MDR_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23502; MAJOR FACILITATOR SUPERFAMILY; 1.
DR PANTHER; PTHR23502:SF74; MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001745};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 103..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 513..532
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 101..535
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 29..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 584 AA; 64290 MW; 985688CBA1EA52C1 CRC64;
MPSDDEIHSE AQLSELMQTV TRTSMLLELE ATPSESGSET TTLRGSAVDS NENPDNNSNN
VTHEAVHGNP SSYRFRRVAS KTIVSFAPDD PENPHNWSTS KKIFVVISGM MQVLNSTIGS
SLPSGAIKYI ARDFNVTDET KLVLPISLFL VGYVLGPLLY GPLSEQYGRR YPLLIGYVLF
DIFVMACALA PTFNALLVFR LFNGMAASAP IAIITGTFSD VFDNPTVRGR TMAWYMSCTA
VGPIISPFMS GFISTVSWRW SFWLGLLIAG TSCPLVILYP ETYGPVLLKS RARELRRKTG
NMSIVAPMDL TPHDLRAVLT VTLTRPIRMI AKEYMVSLTC LYCALAYAIF YLYFQAYPLI
FEGIYGMSTG IAGLIYLPIA LGCFLACGIF IWYDGFLARA KARGTSWAQN EDYRRLPLAC
VGGPLYVISL FWLGWTASPN VHWAVPMCSG IIFGLAYELI FMAMLNYLSD AYQVFAASAQ
SASSCCRSIL GAVLPLAAKP MFSAVGIDWG CSIIGFASLG VSVIPFGFIY FGERIRNGSK
LMQHLKALRE EEQRAWEAEQ HGLQRVQQGT GDIEKGLQAT VVSR
//
