ID B8M213_TALSN Unreviewed; 505 AA.
AC B8M213;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE SubName: Full=MFS transporter, putative {ECO:0000313|EMBL:EED21391.1};
GN ORFNames=TSTA_086220 {ECO:0000313|EMBL:EED21391.1};
OS Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS 1006) (Penicillium stipitatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441959 {ECO:0000313|EMBL:EED21391.1, ECO:0000313|Proteomes:UP000001745};
RN [1] {ECO:0000313|Proteomes:UP000001745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC {ECO:0000313|Proteomes:UP000001745};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; EQ962653; EED21391.1; -; Genomic_DNA.
DR RefSeq; XP_002478354.1; XM_002478309.1.
DR AlphaFoldDB; B8M213; -.
DR GeneID; 8104587; -.
DR VEuPathDB; FungiDB:TSTA_086220; -.
DR eggNOG; KOG2533; Eukaryota.
DR HOGENOM; CLU_001265_0_1_1; -.
DR InParanoid; B8M213; -.
DR OMA; QRRKYMG; -.
DR OrthoDB; 1405370at2759; -.
DR PhylomeDB; B8M213; -.
DR Proteomes; UP000001745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17327; MFS_FEN2_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR43791:SF24; HIGH-AFFINITY NICOTINIC ACID TRANSPORTER; 1.
DR PANTHER; PTHR43791; PERMEASE-RELATED; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001745};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 134..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..474
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 505 AA; 56264 MW; 91A240D80F855B23 CRC64;
MADNHHEKNT EDVESNVPMQ PINEKQKQPT QNLSDGNLSV QSVSDLVNVQ LDPVKEKKLL
AKLDLHFVPI IMFAYLTCFL DRGNIGNVKV AGMPEDIGAS AAQYSTAVSI FYATYVTFET
PLAMLMKKIT PRNLLCGLCV VWSLTTIFTG FVTSVGGLYA SRLVLGCCEA GLFPCLNLYI
SMVYRREEQA KRVSYLMSCA ALSGAVGGLL AYGLLQMDGV AGKAGWRWVY IIEGLFSIVV
AVWVWFGLPN DPTNAYFLTT EQRWMMQVRN EQSRQYLGPE KFTWDQFWIE VRDPKLYFSA
ATQFCQDILL YGFSTFLPAI LKSMGYNTLK SNALTVPVYI WGVISFTILA WWADRVTRFV
PFLLGANAIS IVGYILLIAV KTNDAVRYFA TYLCVVACYL GPGLNIAWLN VNVAPHHRRA
VAIGLQQTIG NTAGIVAGQV YRKSPYILGN SFSLGSVCVA QLLIVAHALY LRREIAAKER
IAEGKVEDKR RVTTGDGAVD YKYFY
//
