ID B8M7N8_TALSN Unreviewed; 703 AA.
AC B8M7N8;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 59.
DE SubName: Full=Amidase, putative {ECO:0000313|EMBL:EED19591.1};
DE EC=6.3.4.6 {ECO:0000313|EMBL:EED19591.1};
GN ORFNames=TSTA_028730 {ECO:0000313|EMBL:EED19591.1};
OS Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS 1006) (Penicillium stipitatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441959 {ECO:0000313|EMBL:EED19591.1, ECO:0000313|Proteomes:UP000001745};
RN [1] {ECO:0000313|Proteomes:UP000001745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC {ECO:0000313|Proteomes:UP000001745};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
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DR EMBL; EQ962654; EED19591.1; -; Genomic_DNA.
DR RefSeq; XP_002480025.1; XM_002479980.1.
DR AlphaFoldDB; B8M7N8; -.
DR STRING; 441959.B8M7N8; -.
DR GeneID; 8098992; -.
DR VEuPathDB; FungiDB:TSTA_028730; -.
DR eggNOG; KOG1211; Eukaryota.
DR HOGENOM; CLU_025343_0_0_1; -.
DR InParanoid; B8M7N8; -.
DR OMA; VECCVTT; -.
DR OrthoDB; 5490475at2759; -.
DR PhylomeDB; B8M7N8; -.
DR Proteomes; UP000001745; Unassembled WGS sequence.
DR GO; GO:0004847; F:urea carboxylase activity; IEA:UniProtKB-EC.
DR CDD; cd00431; cysteine_hydrolases; 1.
DR Gene3D; 1.20.58.1700; -; 1.
DR Gene3D; 3.90.1300.10; Amidase signature (AS) domain; 1.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR InterPro; IPR000120; Amidase.
DR InterPro; IPR023631; Amidase_dom.
DR InterPro; IPR036928; AS_sf.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR PANTHER; PTHR11895:SF169; GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE; 1.
DR PANTHER; PTHR11895; TRANSAMIDASE; 1.
DR Pfam; PF01425; Amidase; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR SUPFAM; SSF75304; Amidase signature (AS) enzymes; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:EED19591.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001745}.
FT DOMAIN 37..226
FT /note="Isochorismatase-like"
FT /evidence="ECO:0000259|Pfam:PF00857"
FT DOMAIN 281..686
FT /note="Amidase"
FT /evidence="ECO:0000259|Pfam:PF01425"
SQ SEQUENCE 703 AA; 75483 MW; CF627D54E5EAF7CB CRC64;
MAATLSIKRI PSGAEDSEVV SFEAQPYAFQ FDPSAAALVI IDMQRDFLLK DGFGYIQAGD
AGVEKVQATI KPTLEVLRKF RERGIHVIHT REGHRPDLRD LPTPKLLRQA RAPNTRHSMV
IGDLGPMGRL LTRGEYGHDI IDELQPVAGE FVIDKPGKGS FFSTTLHEHL VDRGITHLIV
AGVTVECCVT TTVREANDRG FDACILRDCT DGFVSTFKSA SLDMIHFSEG LFGFVSESQP
LLAALSSFPP HPKNLALDWD GSMSIEALKN AYSSGLSPVT VVRHVLKKIS ADKPQHSAVW
LSLASSKNLL GRAEDLERSG DCNLPLFGVP FAVKDNIDVS GLPTTAACPG FEYVPEKSAF
VVTKLEAAGA IVIGKTNLDQ FATGLVGTRS PYGACYCTFS PRHISGGSSS GSAVAVALGH
VSFALGTDTA GSGRIPASFN NIVGLKPTKG TVSTAGVLPA CRTLDCVSFF ASTISDARIA
WLAAKAHDPE DPYARSSPSL ASLNSRSVLH GDALSPAYQE QFAKVLSLVR GLANIEEVNF
DWSAYLAASD LLYKSALVTE RTAAVQELLG SKAKRISLHP VTQKVLDSAS SKTATDVFRD
VHKAQRLLKV IEAEFDKCDI LVVPTAPNHP TVAEVEQDPI VPNLKLGIFA SAVNILDLAA
VAIPAEHIDG LPFGISIIAP AFREGFILKV AERIRKRMEH FVL
//
