ID B8MM99_TALSN Unreviewed; 1060 AA.
AC B8MM99;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Methyltransferase type 11 domain-containing protein {ECO:0000259|Pfam:PF08241};
GN ORFNames=TSTA_099080 {ECO:0000313|EMBL:EED13653.1};
OS Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS 1006) (Penicillium stipitatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441959 {ECO:0000313|EMBL:EED13653.1, ECO:0000313|Proteomes:UP000001745};
RN [1] {ECO:0000313|Proteomes:UP000001745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC {ECO:0000313|Proteomes:UP000001745};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
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DR EMBL; EQ962658; EED13653.1; -; Genomic_DNA.
DR RefSeq; XP_002485891.1; XM_002485846.1.
DR AlphaFoldDB; B8MM99; -.
DR STRING; 441959.B8MM99; -.
DR GeneID; 8103986; -.
DR VEuPathDB; FungiDB:TSTA_099080; -.
DR eggNOG; ENOG502RDBT; Eukaryota.
DR HOGENOM; CLU_005788_0_0_1; -.
DR InParanoid; B8MM99; -.
DR OMA; RTELWLM; -.
DR OrthoDB; 2056330at2759; -.
DR PhylomeDB; B8MM99; -.
DR Proteomes; UP000001745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR013216; Methyltransf_11.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF08241; Methyltransf_11; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001745};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 991..1013
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 771..821
FT /note="Methyltransferase type 11"
FT /evidence="ECO:0000259|Pfam:PF08241"
FT REGION 61..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 98..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 188..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 523..566
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1060 AA; 117677 MW; E95BAE956085702B CRC64;
MADSHHRQVA TLSSPLRLAR KPLLNTIMEA NENSPGEQQS VRHEMTRESL HSIQIAMSFS
PETARRISTP VDTLSSSSSS CSDEEWQQGL RPFDDLYDAS DDDERNCPSL TDSRPSSLAT
MSIRSSTYST NSRNRYPSLM IPTASLWPSL VNPHKSSPVP PTPPPKIPVS PAALSMLPGN
VPAIHAPPSL DGSLSSDQIS NISSPATPDL RPVRDHDWDN EIIRVRQDPT APSSAGASST
DLTTDEERAI ETSVDDWNPL LDSFPAIPAG FESHEPAVLS PDDQHNNPVS PRSESPELDG
ITLPPAAIAT LQHIPLDSTP GPWSETSEKN DEMWQLATPP TNRQQRNSPP PDATPDSELS
GYSFTNLSIP SPGGFFSSLD PKSRYTWSLP SVVNPPTTAV AARFYDLPWG LDQGEVVEQV
VEVAVDQNIA EDQPTAVPIT AIRIPSAQHK RSDSHDSSSP VVADVEELDR SGVPAYEYDE
AYDDELKRQA VANLDRTSVW LAAQHSYLSA LSETNPVNVV EANKKPEPLE VENRPVSSSG
HSPPRKSVRF SEDVQELTMS PLPPPPEDMS KDSIYWRGFQ FVLQQSRRRD VFLHSDIRFD
AVQSVRLGFP QKHRAALLGK FELEAPERPG YKGPFSQAPR KSVLAEVLAE QALYSNLEKE
QMVLSQLYQS MWAVDASRFL NGGRLISRPA AKRLSTILKQ MDNPQLGTIA PKRRLRVLDL
GGQATCGWAW QLAHDYPDVK VYTVVGKNQE VNSHIKGPAN HRRVSVPCLW KLPFRNNQFD
VISARSLHAL LKTERPAGEE LDEYDLCLKE CYRCLKPGGY LEFFTMDSSI ARAGPLGTAA
SVEFTFNLKT RGYDPSPTRG FLSRLQRSNF ADIKRAWLFL PMGIEPIKPE PMRETPNPRV
KSQIDCEAIQ GPVGSTADVA SMTGLLGGWM WEQWLLKIQM EMGREENDLL KDIGGVFDEG
RKLNAGWTCL SGWAMKPTRR STMMMMMMNR VFLPNLKIII LCAGFTEYMY LFLKLYAGHV
TPEQTRATLS AARFRPLQPS ETKQLQRLLS ITIIASGIVL
//
