ID B8N0I3_ASPFN Unreviewed; 813 AA.
AC B8N0I3;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Glycosyl hydrolase, putative {ECO:0000313|EMBL:EED55155.1};
GN ORFNames=AFLA_024260 {ECO:0000313|EMBL:EED55155.1};
OS Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS / JCM 12722 / SRRC 167).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=332952 {ECO:0000313|EMBL:EED55155.1, ECO:0000313|Proteomes:UP000001875};
RN [1] {ECO:0000313|EMBL:EED55155.1, ECO:0000313|Proteomes:UP000001875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 /
RC SRRC 167 {ECO:0000313|Proteomes:UP000001875};
RX PubMed=25883274; DOI=10.1128/genomeA.00168-15;
RA Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT aflatoxin contamination of food and feed.";
RL Genome Announc. 3:E0016815-E0016815(2015).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EQ963473; EED55155.1; -; Genomic_DNA.
DR RefSeq; XP_002373937.1; XM_002373896.1.
DR AlphaFoldDB; B8N0I3; -.
DR STRING; 332952.B8N0I3; -.
DR EnsemblFungi; EED55155; EED55155; AFLA_024260.
DR VEuPathDB; FungiDB:AFLA_000268; -.
DR eggNOG; KOG2230; Eukaryota.
DR HOGENOM; CLU_005015_2_4_1; -.
DR OMA; AWPNLHW; -.
DR UniPathway; UPA00280; -.
DR Proteomes; UP000001875; Unassembled WGS sequence.
DR GO; GO:0004567; F:beta-mannosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0052761; F:exo-1,4-beta-D-glucosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR043534; EBDG/EBM.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR041351; Ig_GlcNase.
DR InterPro; IPR041447; Mannosidase_ig.
DR PANTHER; PTHR43536; MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43536:SF1; MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF18368; Ig_GlcNase; 1.
DR Pfam; PF17786; Mannosidase_ig; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 3.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EED55155.1}.
FT DOMAIN 33..137
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 158..258
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 608..690
FT /note="Mannosidase Ig/CBM-like"
FT /evidence="ECO:0000259|Pfam:PF17786"
FT DOMAIN 702..805
FT /note="Exo-beta-D-glucosaminidase Ig-fold"
FT /evidence="ECO:0000259|Pfam:PF18368"
SQ SEQUENCE 813 AA; 92037 MW; DBCD0DC1A3E8DF2E CRC64;
MAGLIQNHVY NDTHLFYSNN LATVDQTIFR APWLYREELR LLAPPKGQHM FLITHGITSK
ADIYFNGKQI ASNATQQGSY GGHRYDITPF VRTGKNVLLI QAHPTNYLRD FAQGFVDWNP
YPPDNGTGVW RDVELKQTGP VSMSSPRILT DFIGVHTENV TATIKVDIKN HEDRIANGVV
HGTVQAQDKG SQTVAFSKQF KLEPYKNATV SIDVVLKNPK IWWPATWGKQ PLYTVKAKTT
VGQNEISDIA PPTQFGIRHV TSKLNSYNDT EFSVNGYPFH VRGGGYSPDM FLRFDLEHLR
NIFRYMLDMG LNTVRLEGKQ EHPELYDLAD RMGLMVMSGW ECCDKWEGWK YNNEANGVKW
TEKDYPIAET TMLHEAEMMQ AHPSMLAFLI GSDFWPDEKA TNVYVNALNR MDWPNPIIAS
ASKRGYPKLL GPSGMKMDGP YDWVPPNYWY HDKLGAAFGF GSEQGPGVGT PELGSLQQFM
SAQELESLWM KPEQPQWHMA KNDSPFADRS LYNEGLFARY GPPTGLEDYL RKSQMSDYEG
TRAEFEAFAI RQNASRPATG VVYWMLNGAW PSLHWQLFDY YLRPAGSYFG TKVGARLEHV
AYDYEAHTVH IINHSLKNFG KRNVTVDLID LNGTSMHHES IATYTTPTSS KQVATVPEIN
KIKDVGFLRL TLKDSVKGTT ISRNVYWLPP NTESLDWDNS TFYTTPVTKY TDLTALNKMP
AANVSTSMKM TVSKHGSTFG EVTLENKSDV PAFFMHLTVS DENGHELAPV YWSDNYVTLF
PREKLILTVE FQGRKWAATL SGANVEKRGI GRS
//
