ID B8NAP5_ASPFN Unreviewed; 1290 AA.
AC B8NAP5;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Pre-mRNA splicing factor (Prp24), putative {ECO:0000313|EMBL:EED52568.1};
GN ORFNames=AFLA_042700 {ECO:0000313|EMBL:EED52568.1}, G4B84_010659
GN {ECO:0000313|EMBL:QMW35168.1};
OS Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS / JCM 12722 / SRRC 167).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=332952 {ECO:0000313|EMBL:EED52568.1, ECO:0000313|Proteomes:UP000001875};
RN [1] {ECO:0000313|EMBL:EED52568.1, ECO:0000313|Proteomes:UP000001875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 /
RC SRRC 167 {ECO:0000313|Proteomes:UP000001875}, and NRRL3357
RC {ECO:0000313|EMBL:EED52568.1};
RX PubMed=25883274; DOI=10.1128/genomeA.00168-15;
RA Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT aflatoxin contamination of food and feed.";
RL Genome Announc. 3:E0016815-E0016815(2015).
RN [2] {ECO:0000313|EMBL:QMW35168.1, ECO:0000313|Proteomes:UP000515286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL3357 {ECO:0000313|EMBL:QMW35168.1,
RC ECO:0000313|Proteomes:UP000515286};
RA Fountain J.C., Clevenger J.P., Nadon B., Youngblood R.C., Korani W.,
RA Chang P.-K., Starr D., Wang H., Isett B., Johnston H.R., Wiggins R.,
RA Chu Y., Agarwal G., Kemerait R.C., Pandey M.K., Bhatnagar D.,
RA Ozias-Akins P., Varshney R.K., Scheffler B.E., Vaughn J.N., Guo B.;
RT "Two New Chromosome-Level Aspergillus flavus Reference Genomes Reveal a
RT Large Insertion Potentially Contributing to Isolate Stress Tolerance and
RT Aflatoxin Production.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EQ963476; EED52568.1; -; Genomic_DNA.
DR EMBL; CP059872; QMW35168.1; -; Genomic_DNA.
DR RefSeq; XP_002377732.1; XM_002377691.1.
DR STRING; 332952.B8NAP5; -.
DR EnsemblFungi; EED52568; EED52568; AFLA_042700.
DR VEuPathDB; FungiDB:AFLA_007828; -.
DR eggNOG; KOG0128; Eukaryota.
DR HOGENOM; CLU_003925_0_0_1; -.
DR OMA; LWARYIL; -.
DR OrthoDB; 3035286at2759; -.
DR Proteomes; UP000001875; Unassembled WGS sequence.
DR Proteomes; UP000515286; Chromosome 7.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd12296; RRM1_Prp24; 1.
DR CDD; cd12299; RRM4_Prp24; 1.
DR CDD; cd00590; RRM_SF; 1.
DR Gene3D; 3.30.70.330; -; 4.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR034397; Prp24_RRM1.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR031766; RRM_occluded.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR48025; OS02G0815200 PROTEIN; 1.
DR PANTHER; PTHR48025:SF22; OS02G0815200 PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 3.
DR Pfam; PF16842; RRM_occluded; 1.
DR SMART; SM00386; HAT; 4.
DR SMART; SM00360; RRM; 4.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50102; RRM; 4.
PE 4: Predicted;
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 831..907
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 906..983
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 997..1073
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 1116..1189
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..825
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1087..1112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1193..1290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 785..816
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1251..1271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1272..1290
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1290 AA; 144726 MW; FD3B8B0DD140F480 CRC64;
MMDINSLLSP QESNSQSGRS SPSAAPTSVS NTSIPSTGPP PKPLRKNRAG QTRQGMTSSP
LAQHVFAPPH VSEPSPPAIS PTVGPNVGSG SGTPPAADLP PPRQPSTPGM DTLADLASMQ
HHQPQRSNAP LLRSTESYES QLSPSTMYPH VSSVAHNTPT PRSSFDIAMS DGPREAARRN
YMDTSLVPNA QRMATELFAQ IQENPQSYDA HVNFVRLLHA GFVNHVYPPN NPDIHGDPRK
YDLLKDMRTA REEMDKLFAM GEDLWAEWIQ DESMLAQTVD ERIVVMELCQ RSVEEEYGST
KLWSIYGEWV LYLYNSAHAE GAQHQWTEED RMIGREVFSW HMVLDVWQRG AEATRWRTPD
SHLVWDRLLD LQVQDITRNP SQEKIGHVRN LFDIRLQTPH ATWDQTFQAF SGFVSTYYNA
NYETIMADTA GRYATSCKEQ YSAREEFEIR LRNATEAGDV TQEWTIFTEY IEWEISNNRR
NHHSNFELVN AVYQRAVLRF PTDANMWEDF VMFLIDESMH GNANTTTIST LERATRHCPC
SGTLWSQYLL SSEREGQSFS KIADIKHKAT STGLLDVAGM EEVLKVHTAW CSYLRRRAFM
PDSTDEDLDV AEVGIRSAIE SVQELGEKKY GRSYQGDPLF RLERIYIRYL SESGSWDSAR
ETFKGLMGRR GNSYEFWLTY YEWELISWSK FVQGEATVDA ARRTPNPSFA TAVLKQAIKR
TDLDWPEKIM QTYIAHCEDY EDSDELQLAI LETRKAMRAV RARRERDARE LAAQHAQQAA
SSEQATHPEK RKREEEEANV NGLPAKKARG EEETSAAEAE PAVLQRDREN ATVVVKNLPH
QISEHKVRQF FRHCGTINSV KMFPGDGNSE VAVIEFNSRD EALVAQTRDQ KSLDGFTIEV
QIGTCSTLFV TNFPPEADEN YIRGLFREYG EIIDVRFPSL KYNTHRRFCY VQFKTAEAAH
SATKLDGTTV GKGLTLTAKI SDPSRKQDRH GPIYEGREIH VSNVDFKASE RDVQELFSKY
GTVELVRLPR KVDGGSKGFG YVVFSNKEEA TAALAMDGQE YRSRTLHVKI SAPQSTKRSA
TTIVSQVGKS QSPAAVVNGS KESADADTPS RERAARSLGL MNIPDTVNDA RIRALVEPYG
KLIKIVLRPD HQGAIVEFAD VNHAGRASLE LEGQEIAPGR KLHVGTVPEM LKQSAENKDG
RIQPSSKPKE KQGGFLQPTG PIKRPQQPGS RGGRRGGLGV KRAGPHGGHN GEKTMTTTMM
TTDSAPSAEG GKTKKSNDDF RAMIQRGREE
//
