ID B8NFA7_ASPFN Unreviewed; 1096 AA.
AC B8NFA7;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Zinc finger protein, cchc domain containing protein, putative {ECO:0000313|EMBL:EED51888.1};
GN ORFNames=AFLA_061510 {ECO:0000313|EMBL:EED51888.1}, G4B84_007630
GN {ECO:0000313|EMBL:QMW32199.1};
OS Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS / JCM 12722 / SRRC 167).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=332952 {ECO:0000313|EMBL:EED51888.1, ECO:0000313|Proteomes:UP000001875};
RN [1] {ECO:0000313|EMBL:EED51888.1, ECO:0000313|Proteomes:UP000001875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 /
RC SRRC 167 {ECO:0000313|Proteomes:UP000001875}, and NRRL3357
RC {ECO:0000313|EMBL:EED51888.1};
RX PubMed=25883274; DOI=10.1128/genomeA.00168-15;
RA Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT aflatoxin contamination of food and feed.";
RL Genome Announc. 3:E0016815-E0016815(2015).
RN [2] {ECO:0000313|EMBL:QMW32199.1, ECO:0000313|Proteomes:UP000515286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL3357 {ECO:0000313|EMBL:QMW32199.1,
RC ECO:0000313|Proteomes:UP000515286};
RA Fountain J.C., Clevenger J.P., Nadon B., Youngblood R.C., Korani W.,
RA Chang P.-K., Starr D., Wang H., Isett B., Johnston H.R., Wiggins R.,
RA Chu Y., Agarwal G., Kemerait R.C., Pandey M.K., Bhatnagar D.,
RA Ozias-Akins P., Varshney R.K., Scheffler B.E., Vaughn J.N., Guo B.;
RT "Two New Chromosome-Level Aspergillus flavus Reference Genomes Reveal a
RT Large Insertion Potentially Contributing to Isolate Stress Tolerance and
RT Aflatoxin Production.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the DNA polymerase type-B-like family.
CC {ECO:0000256|ARBA:ARBA00008593}.
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DR EMBL; EQ963477; EED51888.1; -; Genomic_DNA.
DR EMBL; CP059870; QMW32199.1; -; Genomic_DNA.
DR RefSeq; XP_002378895.1; XM_002378854.1.
DR AlphaFoldDB; B8NFA7; -.
DR EnsemblFungi; EED51888; EED51888; AFLA_061510.
DR VEuPathDB; FungiDB:AFLA_005206; -.
DR eggNOG; KOG2277; Eukaryota.
DR HOGENOM; CLU_002806_0_0_1; -.
DR OMA; PYQHARN; -.
DR OrthoDB; 170176at2759; -.
DR Proteomes; UP000001875; Unassembled WGS sequence.
DR Proteomes; UP000515286; Chromosome 5.
DR GO; GO:1990817; F:poly(A) RNA polymerase activity; IEA:UniProtKB-EC.
DR CDD; cd05402; NT_PAP_TUTase; 1.
DR Gene3D; 1.10.1410.10; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002058; PAP_assoc.
DR InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR PANTHER; PTHR12271; POLY A POLYMERASE CID PAP -RELATED; 1.
DR PANTHER; PTHR12271:SF113; POLY(A) RNA POLYMERASE CID11-RELATED; 1.
DR Pfam; PF01909; NTP_transf_2; 1.
DR Pfam; PF03828; PAP_assoc; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81631; PAP/OAS1 substrate-binding domain; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 169..211
FT /note="Polymerase nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF01909"
FT DOMAIN 365..420
FT /note="PAP-associated"
FT /evidence="ECO:0000259|Pfam:PF03828"
FT REGION 1..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 592..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 636..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 798..1096
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..94
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 502..533
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 592..616
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 663..739
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 798..826
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 861..903
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 922..940
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 946..974
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1005..1036
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1038..1062
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1096 AA; 120687 MW; 089E382908A60361 CRC64;
MISDVHGNAK LASGPGGKSP IASEKASTMP WNLSTDTSSE APTRPPLNSQ QSNSLPSTPY
QHARNLSFHS RSPSPPHGST SPRSTHSEST HLPPSLRKPF SGCKYETAMA FFRRRIPYSL
GADLLPEERE GLKERLEPEE EKRLTDNMLE VYDRLLPSAE SDDRRRQLVR KLERLFNEQW
PGRDIKVHVF GSSGNKLCSS DSDVDICITT TYKELEQVCL LAEVLARHGM ERVVCVSHAK
VPIVKIWDPE LQLACDMNVN NTLALDNTRM VRTYVEIDER VRPLAMIIKH WTKRRILCDA
GLGGTLSSYT WICLIINFLQ TRNPPILPSL QARPHEKKIS PEGLVCSFDD DLGNLTGYGR
KNKQSLGDLF FQFFKYYGHE LDYEKYVVSV REGKLISKEA KGWHLLQNNR LCVEEPFNTS
RNLGNTADDT SFRGVHLELR RAFKAASQGD LELCCEQYEY PPEEERSWER PPPQPRPVLT
APPSSRGGRG GGRGGRNSHQ YPRGGHNGSR RSSNTPHKSN NFRQASNGMS ASELSLQAQQ
AQYLLHDHLY QQIQILQAQE QELRLQLQNQ ALLTGRPPPV LIRQPFIQFP MPQQQESTGD
DNSRSRSGTA NHAPHGTQLR QHVYYGTPYL PVAITGLQGS STTNPPSPSA PTAMPELRRN
PRRSSVANGS PGGSLRAQSQ PARSVHSLPS FAPIYSMTQD PPQGSKQRNT PVSPDGAPNE
EDNNFMPSSM PNVSRSPYLD ESRPTEYMGY YLATSPQLQT YHQNAMLSPL QTPVGLALPN
GGIMPFVANP QEYLSTFGPQ DAFASSPDNG STQASKAGST HQRATARPMA SGGPLIVDGS
VPLSEPRNTA PSAENYDPYG AMSHCTSTSD DHNTDTPASV SDSFSQDYQD TSSVETDQTP
YFGRQGIDTR KPADALTNGH GGKPSLLSSR LQSLHLSNSE KMAEPPSKLG PEKHKAAFSH
QETSEKDSSR LRHTTAEKVM SGPELQGASN GKRRTNGVDV PEKVNGNSHK SKPKNRSDTS
HPTGGPGDKE RNGGHPRRTN GAGSTTHDSH GNHTSSGWQT TKKKQKKNAR SNAESRHGFH
GGAEPLPADE SLRKGG
//
