ID B8NSL9_ASPFN Unreviewed; 423 AA.
AC B8NSL9;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Salicylate hydroxylase, putative {ECO:0000313|EMBL:EED46917.1};
GN ORFNames=AFLA_049700 {ECO:0000313|EMBL:EED46917.1}, G4B84_000443
GN {ECO:0000313|EMBL:QMW25198.1};
OS Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS / JCM 12722 / SRRC 167).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=332952 {ECO:0000313|EMBL:EED46917.1, ECO:0000313|Proteomes:UP000001875};
RN [1] {ECO:0000313|EMBL:EED46917.1, ECO:0000313|Proteomes:UP000001875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 /
RC SRRC 167 {ECO:0000313|Proteomes:UP000001875}, and NRRL3357
RC {ECO:0000313|EMBL:EED46917.1};
RX PubMed=25883274; DOI=10.1128/genomeA.00168-15;
RA Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT aflatoxin contamination of food and feed.";
RL Genome Announc. 3:E0016815-E0016815(2015).
RN [2] {ECO:0000313|EMBL:QMW25198.1, ECO:0000313|Proteomes:UP000515286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL3357 {ECO:0000313|EMBL:QMW25198.1,
RC ECO:0000313|Proteomes:UP000515286};
RA Fountain J.C., Clevenger J.P., Nadon B., Youngblood R.C., Korani W.,
RA Chang P.-K., Starr D., Wang H., Isett B., Johnston H.R., Wiggins R.,
RA Chu Y., Agarwal G., Kemerait R.C., Pandey M.K., Bhatnagar D.,
RA Ozias-Akins P., Varshney R.K., Scheffler B.E., Vaughn J.N., Guo B.;
RT "Two New Chromosome-Level Aspergillus flavus Reference Genomes Reveal a
RT Large Insertion Potentially Contributing to Isolate Stress Tolerance and
RT Aflatoxin Production.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the paxM FAD-dependent monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00007992}.
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DR EMBL; EQ963483; EED46917.1; -; Genomic_DNA.
DR EMBL; CP059866; QMW25198.1; -; Genomic_DNA.
DR RefSeq; XP_002383097.1; XM_002383056.1.
DR AlphaFoldDB; B8NSL9; -.
DR STRING; 332952.B8NSL9; -.
DR EnsemblFungi; EED46917; EED46917; AFLA_049700.
DR VEuPathDB; FungiDB:AFLA_010844; -.
DR eggNOG; KOG2614; Eukaryota.
DR HOGENOM; CLU_009665_19_5_1; -.
DR OMA; IAGYCPT; -.
DR OrthoDB; 5491711at2759; -.
DR Proteomes; UP000001875; Unassembled WGS sequence.
DR Proteomes; UP000515286; Chromosome 1.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR13789:SF317; HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17670)-RELATED; 1.
DR PANTHER; PTHR13789; MONOOXYGENASE; 1.
DR Pfam; PF01494; FAD_binding_3; 2.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 7..200
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
FT DOMAIN 304..367
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 423 AA; 46794 MW; 85A6D335161C49A2 CRC64;
MSEHRKAIII GGGPAGLSTA LRLHQTTNVK CTIYELRPEP TTLGGAIGIM PNGLQLFSRL
GVYDALHARG SSQSNLVIHS AQGGIVGEQK DMVSYARAQT GFGYLRIKRT DLVDVLLDAV
YKAQIPIYFK KRLTTIDDNG DSGVTMTFSD GSTDTADILI GCDGIHSCVR RLYVDPNQRP
EYSGFSGLFS LVPTSRLSSS AAAQVSGIGA TLTEQGMFMV MLATAAGDEV SWGLSQEVPL
PDSGDSRDGW EVYRQKELNG FKSNMHQILE KVHGDWGDLL KQLVENTDVM KFYPVYRLPL
GGAWYRGRCV LLGDAAHAMQ PHAGQGVSMA LEDTFLLARL LEDHSRPLTE VYKKYEEIRR
PRVNEIYKLA SRNAGVRKTT GPWGLWSKEV VVGMAFWASW ALGLEKWGWR QKHMAYDIDM
EEI
//
