ID B8NSM4_ASPFN Unreviewed; 588 AA.
AC B8NSM4;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Flavin-binding monooxygenase-like protein {ECO:0000313|EMBL:EED46922.1};
GN ORFNames=AFLA_049750 {ECO:0000313|EMBL:EED46922.1}, G4B84_000436
GN {ECO:0000313|EMBL:QMW25191.1};
OS Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS / JCM 12722 / SRRC 167).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=332952 {ECO:0000313|EMBL:EED46922.1, ECO:0000313|Proteomes:UP000001875};
RN [1] {ECO:0000313|EMBL:EED46922.1, ECO:0000313|Proteomes:UP000001875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 /
RC SRRC 167 {ECO:0000313|Proteomes:UP000001875}, and NRRL3357
RC {ECO:0000313|EMBL:EED46922.1};
RX PubMed=25883274; DOI=10.1128/genomeA.00168-15;
RA Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT aflatoxin contamination of food and feed.";
RL Genome Announc. 3:E0016815-E0016815(2015).
RN [2] {ECO:0000313|EMBL:QMW25191.1, ECO:0000313|Proteomes:UP000515286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL3357 {ECO:0000313|EMBL:QMW25191.1,
RC ECO:0000313|Proteomes:UP000515286};
RA Fountain J.C., Clevenger J.P., Nadon B., Youngblood R.C., Korani W.,
RA Chang P.-K., Starr D., Wang H., Isett B., Johnston H.R., Wiggins R.,
RA Chu Y., Agarwal G., Kemerait R.C., Pandey M.K., Bhatnagar D.,
RA Ozias-Akins P., Varshney R.K., Scheffler B.E., Vaughn J.N., Guo B.;
RT "Two New Chromosome-Level Aspergillus flavus Reference Genomes Reveal a
RT Large Insertion Potentially Contributing to Isolate Stress Tolerance and
RT Aflatoxin Production.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|ARBA:ARBA00009183}.
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DR EMBL; EQ963483; EED46922.1; -; Genomic_DNA.
DR EMBL; CP059866; QMW25191.1; -; Genomic_DNA.
DR RefSeq; XP_002383102.1; XM_002383061.1.
DR AlphaFoldDB; B8NSM4; -.
DR EnsemblFungi; EED46922; EED46922; AFLA_049750.
DR VEuPathDB; FungiDB:AFLA_010852; -.
DR eggNOG; KOG1399; Eukaryota.
DR HOGENOM; CLU_019225_1_0_1; -.
DR OMA; WISPFWI; -.
DR OrthoDB; 1434032at2759; -.
DR Proteomes; UP000001875; Unassembled WGS sequence.
DR Proteomes; UP000515286; Chromosome 1.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000960; Flavin_mOase.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR23023; DIMETHYLANILINE MONOOXYGENASE; 1.
DR PANTHER; PTHR23023:SF292; FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_6G01900); 1.
DR Pfam; PF00743; FMO-like; 1.
DR PIRSF; PIRSF000332; FMO; 3.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033, ECO:0000313|EMBL:EED46922.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
SQ SEQUENCE 588 AA; 65544 MW; 0DC7CAB4AA52442D CRC64;
METVDVTVIG AGWSGLAALK TYHQVDPSAS IVLFESAASV GGVWAKHRLY AGLKSNNMLG
TYEFSDFPMD ASFGVQPGQH IPGTVIQQYM ERFVEHFQLS EFIRLNTRVR IAEHNSDGTW
TLTIDDTDGE KTVVSKKLIV CTGITSQPYM PTITGQDTFD APLFHCRDLP QHQDAVLQPN
KRITVLGGTK SAWDAVYAAA TAGAHVDWII RDNGHGPVWM APAYVTPLKK WLEKLVTTRL
LTWFSPCIWG DADGCSPIRN FLHGTWLGRK IVDTFWSILA NDVITLNKYD SHPETKKLKP
WFSPFWIASG LSILNYPTNF FDLVTEGKVQ IHIDHITHLT PKTIHLASGS QIQSDTLICA
TGWQATPNID FRPSTLSQTL GFPWAEDPIP QSVIQQADAE ILSRFPRLAT PPPKPANYAP
LAPDAPAAAK HPFRLARLMI PPALANTRSI AFMGLAMTIN TTMLAQAQAL WISAYFTENL
TPAPREQCPP HLRKVLEQDN ADGDADLVWE TALHSQFGVH RYRGGFGKRN PDFVFDAVPY
VDLLLRDLGL DYTRKGGLKW LEPYGVEDYR GLVEEWIDSK EKVGKKDN
//
