ID B8P2D8_POSPM Unreviewed; 1122 AA.
AC B8P2D8;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EED84913.1};
GN ORFNames=POSPLDRAFT_93121 {ECO:0000313|EMBL:EED84913.1};
OS Postia placenta (strain ATCC 44394 / Madison 698-R) (Brown rot fungus)
OS (Poria monticola).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Postiaceae; Postia.
OX NCBI_TaxID=561896 {ECO:0000313|Proteomes:UP000001743};
RN [1] {ECO:0000313|EMBL:EED84913.1, ECO:0000313|Proteomes:UP000001743}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 44394 / Madison 698-R {ECO:0000313|Proteomes:UP000001743};
RX PubMed=19193860; DOI=10.1073/pnas.0809575106;
RA Martinez D., Challacombe J., Morgenstern I., Hibbett D., Schmoll M.,
RA Kubicek C.P., Ferreira P., Ruiz-Duenas F.J., Martinez A.T., Kersten P.,
RA Hammel K.E., Vanden Wymelenberg A., Gaskell J., Lindquist E., Sabat G.,
RA Splinter BonDurant S., Larrondo L.F., Canessa P., Vicuna R., Yadav J.,
RA Doddapaneni H., Subramanian V., Pisabarro A.G., Lavin J.L., Oguiza J.A.,
RA Master E., Henrissat B., Coutinho P.M., Harris P., Magnuson J.K.,
RA Baker S.E., Bruno K., Kenealy W., Hoegger P.J., Kuees U., Ramaiya P.,
RA Lucas S., Salamov A., Shapiro H., Tu H., Chee C.L., Misra M., Xie G.,
RA Teter S., Yaver D., James T., Mokrejs M., Pospisek M., Grigoriev I.V.,
RA Brettin T., Rokhsar D., Berka R., Cullen D.;
RT "Genome, transcriptome, and secretome analysis of wood decay fungus Postia
RT placenta supports unique mechanisms of lignocellulose conversion.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:1954-1959(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|RuleBase:RU003857}.
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DR EMBL; EQ966243; EED84913.1; -; Genomic_DNA.
DR RefSeq; XP_002469834.1; XM_002469789.1.
DR AlphaFoldDB; B8P2D8; -.
DR KEGG; ppl:POSPLDRAFT_93121; -.
DR HOGENOM; CLU_009214_0_0_1; -.
DR InParanoid; B8P2D8; -.
DR OMA; NHANGRR; -.
DR OrthoDB; 5010334at2759; -.
DR Proteomes; UP000001743; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF291; POTASSIUM CHANNEL SUBFAMILY K MEMBER 18; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001743};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 147..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 664..684
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 691..710
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 722..741
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 326..398
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 674..742
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT REGION 42..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 593..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 775..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 937..963
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1103..1122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..75
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..626
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..792
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1122 AA; 122786 MW; 531317299C1298F7 CRC64;
MTLATILAAM HLRPLLGKWR RTPDEYDVEK VTALDNLDDR LANGTRTEDV NLDNDGEDEE
REEEDVQEVD DVEQDDAETG QRAAQSRSRR MRRFTTFASG STFTTFTRSS RSSTRSWLAR
VRSFLLPRDP KPEEIEQYVP TYRSSPIIAG VLIPFSILLE VPGLTEHWYI MTESNNIVDS
RPNPALLNAG MGISIACAVF ANICLIMRFA ERWVKPTTLL CILFLTVHVS VMAADGVNIA
AVTCFGIVHA KNDGYTYGQA FWMTLCSTIV STITNINLVM DYARVRDFAR SGTCGWPQST
VYGTVSSSPP GSGLTRKQRS LVILVIILLM YLALGALINA ELLGISYING LYFSTVCIEV
IGFGDIVPRS TGARVFVCGY IACGMVILGT VISITRDTVL EGLEVGYRKR LQNMRARRAG
ARRFRHWQRR WRDAVVWRLR AQSKPVWVPD TDWQHGDDAV RFVGLGGPGG GGGREPLLGR
ALEALGLRDP PPSDPSMRPA QHVPGHPRGM HLNINALTHN ELEAAALEAG VPLNQFTEVS
EARQIAASGG RPTGRGPLPD GGWPAQVGTP TDAQVGRMAA MLTEVSLAMS GRDIRLPGPS
AQDRSNPRAA VVEEHANRGD EQRRNEANDA IVQREGEATD SAGYAAESKW IPVDMKDEEQ
NANVMKLSVA WTVFFVFWFA GAAIFSATEK WTYGVALYFC WICFTTAGFG DYAPATPAGR
SVFVFWALFG VGTLTMLVAV IEDAGSTRYK AAMHSRAFDK AVAKYRKKAA LKATKAASRA
EHSTQRVTNA SDMTAEEGAA EAAEPDSSGL VLTASKLEEV QAQTQRHLEA LPHEIIHRAR
TFHDYMQYFA GGRGRDLPGE GPQTNVPDEL RKLLDEIVRS EGIGERVKRD ILQDKDAKNT
LFLLSVERAL RKMIGSAEQA LEVLANRNTL LAQFEAQKPT NDDDGAVYEG PTPSGSAASQ
QSTNRPILTP EVATPSSQSQ TASSRHLLAQ CLRSGILSQD TLVGPEKLKK PVPVVAVCDL
LGHGIYIDQI EESGNAVAAG ARLHLFQIAR IMVSDGCPSC WGINFSLEFS NHQRKQDEGD
LEEQRHNGNC ILDSPVDQTT VSEAPDADTL PGGLRHPIGM VL
//
