ID B8PRB1_CARAU Unreviewed; 112 AA.
AC B8PRB1;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Insulin receptor a {ECO:0000313|EMBL:ABV68762.1};
DE Flags: Fragment;
GN Name=IRa {ECO:0000313|EMBL:ABV68762.1};
OS Carassius auratus (Goldfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Cyprininae; Carassius.
OX NCBI_TaxID=7957 {ECO:0000313|EMBL:ABV68762.1};
RN [1] {ECO:0000313|EMBL:ABV68762.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21701804;
RA Kong X., Wang X., He S.;
RT "Molecular variation and evolution of the tyrosine kinase domains of
RT insulin receptor IRa and IRb genes in Cyprinidae.";
RL Sci. China Life Sci. 54:626-633(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
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DR EMBL; EU009572; ABV68762.1; -; Genomic_DNA.
DR AlphaFoldDB; B8PRB1; -.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR InterPro; IPR020635; Tyr_kinase_cat_dom.
DR PANTHER; PTHR24416:SF535; INSULIN RECEPTOR; 1.
DR PANTHER; PTHR24416; TYROSINE-PROTEIN KINASE RECEPTOR; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR00109; TYRKINASE.
DR SMART; SM00219; TyrKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840};
KW Receptor {ECO:0000313|EMBL:ABV68762.1}.
FT DOMAIN 1..112
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABV68762.1"
FT NON_TER 112
FT /evidence="ECO:0000313|EMBL:ABV68762.1"
SQ SEQUENCE 112 AA; 12450 MW; B9967B83E5D8A72A CRC64;
TVNESASLRE RIEFLNEASV MKAFSCHHVV RLLGVVSKGQ PTLVVMELMT HGDLKSFLRS
LRPDSENNPG RPPPTLKEMV QMAAEIADGM AYLNAKKFVH RDLAARNCMV AE
//
