ID B8R919_9BACT Unreviewed; 151 AA.
AC B8R919;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=siroheme decarboxylase {ECO:0000256|ARBA:ARBA00023471};
DE EC=4.1.1.111 {ECO:0000256|ARBA:ARBA00023471};
OS uncultured bacterium 2303.
OC Bacteria; environmental samples.
OX NCBI_TaxID=548900 {ECO:0000313|EMBL:ACF98175.1};
RN [1] {ECO:0000313|EMBL:ACF98175.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=19011059; DOI=10.1128/AEM.01706-08;
RA Demaneche S., Philippot L., David M.M., Navarro E., Vogel T.M., Simonet P.;
RT "Characterization of denitrification gene clusters of soil bacteria via a
RT metagenomic approach.";
RL Appl. Environ. Microbiol. 75:534-537(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 H(+) + siroheme = 12,18-didecarboxysiroheme + 2 CO2;
CC Xref=Rhea:RHEA:19093, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:60052, ChEBI:CHEBI:140497; EC=4.1.1.111;
CC Evidence={ECO:0000256|ARBA:ARBA00023409};
CC -!- PATHWAY: Porphyrin-containing compound metabolism.
CC {ECO:0000256|ARBA:ARBA00023444}.
CC -!- SIMILARITY: Belongs to the Ahb/Nir family.
CC {ECO:0000256|ARBA:ARBA00023457}.
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DR EMBL; EU910857; ACF98175.1; -; Genomic_DNA.
DR AlphaFoldDB; B8R919; -.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 3.30.70.3460; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000485; AsnC-type_HTH_dom.
DR InterPro; IPR040523; AsnC_trans_reg2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR43413:SF1; SIROHEME DECARBOXYLASE NIRL SUBUNIT; 1.
DR PANTHER; PTHR43413; TRANSCRIPTIONAL REGULATOR, ASNC FAMILY; 1.
DR Pfam; PF17805; AsnC_trans_reg2; 1.
DR Pfam; PF13404; HTH_AsnC-type; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239}.
FT DOMAIN 6..48
FT /note="HTH asnC-type"
FT /evidence="ECO:0000259|Pfam:PF13404"
FT DOMAIN 71..143
FT /note="Siroheme decarboxylase AsnC-like ligand binding"
FT /evidence="ECO:0000259|Pfam:PF17805"
SQ SEQUENCE 151 AA; 16147 MW; 51475EB3C68A69C3 CRC64;
MSALADPVDR AIVNALQADF PLCERPFAAA AQRLGLVEDD LIARIDRLLA DGTLTRFGPL
FDAGRMGGGY TLAAMAVAAD DVEGVAAIVN GFPEVAHHYL REHALNLWFV VAAPTPAAID
DAVARIEQAA GVPVLAFPKE REYFVTMMLR A
//
