ID   B8XIU5_9CALI            Unreviewed;       184 AA.
AC   B8XIU5;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=RNA-dependent RNA polymerase {ECO:0000313|EMBL:ACL15044.1};
DE   Flags: Fragment;
OS   Norovirus Hu/GII/2005/6742/Chelyabinsk/RUS.
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
OX   NCBI_TaxID=572446 {ECO:0000313|EMBL:ACL15044.1};
RN   [1] {ECO:0000313|EMBL:ACL15044.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=6742 {ECO:0000313|EMBL:ACL15044.1};
RA   Podkolzin A., Abramycheva N., Braslavskaya S., Fenske E.;
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-
CC         diphosphate + H(+) + phosphate; Xref=Rhea:RHEA:23680,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:57930, ChEBI:CHEBI:61557; EC=3.6.1.15;
CC         Evidence={ECO:0000256|ARBA:ARBA00001491};
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DR   EMBL; FJ383864; ACL15044.1; -; Genomic_RNA.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 1.20.960.20; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR004004; Helic/Pol/Pept_Calicivir-typ.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001205; RNA-dir_pol_C.
DR   Pfam; PF00680; RdRP_1; 1.
DR   PRINTS; PR00918; CALICVIRUSNS.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000313|EMBL:ACL15044.1}; Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT   DOMAIN          11..136
FT                   /note="RNA-directed RNA polymerase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00680"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ACL15044.1"
SQ   SEQUENCE   184 AA;  20928 MW;  8F088D867AC91724 CRC64;
     LSPDTIQANS LFSFYGDDEI VSTDIKLDPE KLTAKLKEYG LKPTRPDKTE GPLVISEDLN
     GLTFLRRTVT RDPAGWFGKL EQSSILRQMY WTRGSNHEDP SETMIPHSQR PIQLMSLLGE
     AALHGPAFYS KISKLVIAEL KEGGMDFYVP RQEPMFRWMR FSDLSTWEGD RNLAPSFVNE
     DGVE
//