ID B8YDH7_SPOEX Unreviewed; 504 AA.
AC B8YDH7;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=unspecific monooxygenase {ECO:0000256|ARBA:ARBA00012109};
DE EC=1.14.14.1 {ECO:0000256|ARBA:ARBA00012109};
GN Name=CYP6B31 {ECO:0000313|EMBL:ASO98002.1};
OS Spodoptera exigua (Beet armyworm) (Noctua fulgens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC Noctuidae; Amphipyrinae; Spodoptera.
OX NCBI_TaxID=7107 {ECO:0000313|EMBL:ACL77781.1};
RN [1] {ECO:0000313|EMBL:ACL77781.1}
RP NUCLEOTIDE SEQUENCE.
RA Tang B., Wang S.G., Zhang W.Q., Zhang F.;
RT "Characterization and expression patterns of a CYP6B cytochrome P450 from
RT Spodoptera exigua.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ASO98002.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=28881445;
RA Hu B., Zhang S.H., Ren M.M., Tian X.R., Wei Q., Mburu D.K., Su J.Y.;
RT "The expression of Spodoptera exigua P450 and UGT genes: tissue specificity
RT and response to insecticides.";
RL Insect Sci. 0:0-0(2017).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an organic molecule + O2 + reduced [NADPH--hemoprotein
CC reductase] = an alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein
CC reductase]; Xref=Rhea:RHEA:17149, Rhea:RHEA-COMP:11964, Rhea:RHEA-
CC COMP:11965, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379,
CC ChEBI:CHEBI:30879, ChEBI:CHEBI:57618, ChEBI:CHEBI:58210,
CC ChEBI:CHEBI:142491; EC=1.14.14.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001025};
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004406}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}. Microsome membrane
CC {ECO:0000256|ARBA:ARBA00004174}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004174}.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; FJ524855; ACL77781.1; -; mRNA.
DR EMBL; KX443427; ASO98002.1; -; mRNA.
DR AlphaFoldDB; B8YDH7; -.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd11056; CYP6-like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24292; CYTOCHROME P450; 1.
DR PANTHER; PTHR24292:SF105; CYTOCHROME P450 9AC1; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 2: Evidence at transcript level;
KW Heme {ECO:0000256|RuleBase:RU000461};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU000461};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000461}.
SQ SEQUENCE 504 AA; 57745 MW; B71B6748A21B52FC CRC64;
MSFLYITLGL SALVYAFYYY FTRTFNYWKS RNVPGPEPIP FFGNIKESVL RQKNIGVVIH
DIYKAFPNEK VVGLYRMTSP CLLVRDLEII KHIMIKDFEV FTDRGVDFSK QGLGQNLFHA
DGETWTALRN RFSPIFTTGK LKNMFYLMNE GADSFVDYVS TECQSRQEFE VHLLLQSYTV
STISACAFGV SYDSLQDKME ALKLVDQVIS SPSYIVELDM MYPGLLRSLN LSLFPKVVMK
FFENLVDNII TQRNGKPSGR NDFIDLILEL REKKEVNSTK FGHSGKTLEI TSDVIAAQAF
VFYVAGYETS ATTMGYMLYQ LAMNPDVQKK LTAEIDEVIQ ANNGQVTYET IKEMKYLNKV
FDETLRMYSI VEPLQRKAVR EYKVPGTDLT IEKDTIVLVS PRGIHYDEKY YEDPEVFNPE
RFDPEVAGNR HPCAYLPFGI GQRNCIGMRF GRLQSQLCIT KLLSKFQVEP SKNTARNLEV
EPHRGIIGPK GGIRLNVIPR KIKS
//
