ID B9BGM9_9BURK Unreviewed; 546 AA.
AC B9BGM9;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Alcohol dehydrogenase [acceptor] {ECO:0000313|EMBL:EED96808.1};
DE EC=1.1.99.- {ECO:0000313|EMBL:EED96808.1};
GN Name=alkJ {ECO:0000313|EMBL:EED96808.1};
GN ORFNames=BURMUCGD1_3310 {ECO:0000313|EMBL:EED96808.1};
OS Burkholderia multivorans CGD1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=513051 {ECO:0000313|EMBL:EED96808.1, ECO:0000313|Proteomes:UP000005493};
RN [1] {ECO:0000313|EMBL:EED96808.1, ECO:0000313|Proteomes:UP000005493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGD1 {ECO:0000313|EMBL:EED96808.1,
RC ECO:0000313|Proteomes:UP000005493};
RX PubMed=23105085; DOI=10.1128/JB.01306-12;
RA Varga J.J., Losada L., Zelazny A.M., Brinkac L., Harkins D., Radune D.,
RA Hostetler J., Sampaio E.P., Ronning C.M., Nierman W.C., Greenberg D.E.,
RA Holland S.M., Goldberg J.B.;
RT "Draft Genome Sequence Determination for Cystic Fibrosis and Chronic
RT Granulomatous Disease Burkholderia multivorans Isolates.";
RL J. Bacteriol. 194:6356-6357(2012).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EED96808.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ACFB01000023; EED96808.1; -; Genomic_DNA.
DR RefSeq; WP_006402968.1; NZ_ACFB01000023.1.
DR AlphaFoldDB; B9BGM9; -.
DR Proteomes; UP000005493; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000313|EMBL:EED96808.1}.
FT DOMAIN 254..268
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 219
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 546 AA; 58766 MW; CA4C773B9003C3F6 CRC64;
MQYDYIIVGG GSGGSSVAAR LADACPDATI ALIEAGPHTE RNLLVNMPVG IAALVPFKLR
TNYGYETVPQ PGLGGRRGYQ PRGRGMGGSS AINAMIYTRG HPSDYDEWAQ LGATGWGWQD
VLPYFRRAEG NQRGADAWHG ADGPLTVSDL RFRNPFSERF IEAAHAAGYP LNDDFNGATQ
EGVGFYQVTH RDGSRCSVAR AYIYGRNRPN LHVITDATVL RVGFDGKRAV GVAVSRNGRI
ETLGARAEVI LSAGAFNSPQ LLMCSGIGPA AQLRRHGIAV VHDAPDVGEN LIDHIDFIIN
TRVNSSDLVG ICLRGIAKMT PALARYFSSR TGMMTSNVAE AGGFIKSDPS LDRPDLQLHF
CTALVDDHNR KMHWGFGYSL HVCALRPYSR GTVALASGDA RDAPLIDPRF FSDSRDLDLL
VRGAQAMRRI LSQPPLASHG GRELYTHPNQ SEAELREAIV AHADTIYHPV GTCRMGSDAR
AVVDPQLRVR GVEGLRVVDA SVMPTLIGGN TNAPSVMIGE RAADFIVAAR KGGVPRDQPA
ATVHGR
//
