ID B9BJI1_9BURK Unreviewed; 593 AA.
AC B9BJI1;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Dihydroxy-acid dehydratase {ECO:0000313|EMBL:EEE09864.1};
GN ORFNames=BURMUCGD2_5237 {ECO:0000313|EMBL:EEE09864.1};
OS Burkholderia multivorans CGD2.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=513052 {ECO:0000313|EMBL:EEE09864.1, ECO:0000313|Proteomes:UP000004535};
RN [1] {ECO:0000313|EMBL:EEE09864.1, ECO:0000313|Proteomes:UP000004535}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGD2 {ECO:0000313|EMBL:EEE09864.1,
RC ECO:0000313|Proteomes:UP000004535};
RX PubMed=23105085; DOI=10.1128/JB.01306-12;
RA Varga J.J., Losada L., Zelazny A.M., Brinkac L., Harkins D., Radune D.,
RA Hostetler J., Sampaio E.P., Ronning C.M., Nierman W.C., Greenberg D.E.,
RA Holland S.M., Goldberg J.B.;
RT "Draft Genome Sequence Determination for Cystic Fibrosis and Chronic
RT Granulomatous Disease Burkholderia multivorans Isolates.";
RL J. Bacteriol. 194:6356-6357(2012).
CC -!- SIMILARITY: Belongs to the IlvD/Edd family.
CC {ECO:0000256|ARBA:ARBA00006486}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEE09864.1}.
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DR EMBL; ACFC01000001; EEE09864.1; -; Genomic_DNA.
DR RefSeq; WP_006403926.1; NZ_ACFC01000001.1.
DR AlphaFoldDB; B9BJI1; -.
DR GeneID; 66529607; -.
DR Proteomes; UP000004535; Unassembled WGS sequence.
DR GO; GO:0016836; F:hydro-lyase activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR Gene3D; 3.50.30.80; IlvD/EDD C-terminal domain-like; 1.
DR InterPro; IPR042096; Dihydro-acid_dehy_C.
DR InterPro; IPR000581; DiOHA_6PGluconate_deHydtase.
DR InterPro; IPR020558; DiOHA_6PGluconate_deHydtase_CS.
DR InterPro; IPR037237; IlvD/EDD_N.
DR PANTHER; PTHR43183:SF1; HYPOTHETICAL DIHYDROXY-ACID DEHYDRATASE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR43183; HYPOTHETICAL DIHYDROXYACID DEHYDRATASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF00920; ILVD_EDD; 1.
DR SUPFAM; SSF143975; IlvD/EDD N-terminal domain-like; 1.
DR SUPFAM; SSF52016; LeuD/IlvD-like; 1.
DR PROSITE; PS00886; ILVD_EDD_1; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
SQ SEQUENCE 593 AA; 63586 MW; 83A19067D7C76B6B CRC64;
MTQSPRRLRS QEWFDDPSHA DMTALYVERF MNYGLTREEL QSGRPIIGIA QTGSDLAPCN
RHHIALAERV KAGIRDAGGI PMEFPVHPLA EQSRRPTAAL DRNLAYLGLV EILHGFPLDG
VVLTTGCDKT TPACLMAAAT VDLPAIVLSG GPMLDGWHEG KRVGSGTVIW HARNLLAAGE
IDYEGFMRLT TASSPSIGHC NTMGTALSMN CLAEALGMSL PGCASIPAAY RERGQMAYAT
GKRIVDLVRD DVRPSQIMTR DAFENAIVVA SALGASTNCP PHLIAIARHM GVELSLADWQ
RVGEQVPLLA NCMPAGEYLG ESFHRAGGVP AILRQLDAAG LIHRGCMTVS GRTIADIVAA
APAADGDVIR PHDAPLKHGA GFIVLSGNFF DSAIMKMSVV GDAFRRTYLS EPGAENVFEA
RAIVFDGPED YRARINDPAL AIDERCILVI RGCGTVGYPG SAEVVNMAPP AELVKRGVES
LPCMGDGRQS GTSASPSILN MSPEAAAGGG LALLRTNDRI RVDLNARRVD VLVPDDELAH
RRESAEFQVP PSQTPWQELY RQFVGQLSTG GCLEPATLYL KVIAERGEPR HSH
//
