ID B9BS86_9BURK Unreviewed; 512 AA.
AC B9BS86;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Transcriptional regulator, GntR family {ECO:0000313|EMBL:EEE06657.1};
GN ORFNames=BURMUCGD2_4254 {ECO:0000313|EMBL:EEE06657.1};
OS Burkholderia multivorans CGD2.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=513052 {ECO:0000313|EMBL:EEE06657.1, ECO:0000313|Proteomes:UP000004535};
RN [1] {ECO:0000313|EMBL:EEE06657.1, ECO:0000313|Proteomes:UP000004535}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGD2 {ECO:0000313|EMBL:EEE06657.1,
RC ECO:0000313|Proteomes:UP000004535};
RX PubMed=23105085; DOI=10.1128/JB.01306-12;
RA Varga J.J., Losada L., Zelazny A.M., Brinkac L., Harkins D., Radune D.,
RA Hostetler J., Sampaio E.P., Ronning C.M., Nierman W.C., Greenberg D.E.,
RA Holland S.M., Goldberg J.B.;
RT "Draft Genome Sequence Determination for Cystic Fibrosis and Chronic
RT Granulomatous Disease Burkholderia multivorans Isolates.";
RL J. Bacteriol. 194:6356-6357(2012).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEE06657.1}.
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DR EMBL; ACFC01000006; EEE06657.1; -; Genomic_DNA.
DR AlphaFoldDB; B9BS86; -.
DR Proteomes; UP000004535; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF2; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 40..108
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT REGION 19..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 512 AA; 55676 MW; 8C2F1A78390368F5 CRC64;
MRVSYTAIQF RQTVLDNRPY SSPPTMIRSA PNPAPPAASR TRVETVMDTL RARISSRTLM
PGARVPSIRM MADALHVSKS TVVDAYERLA SEGVLVARRG SGFYVSGHAP PLALADLGPR
LDRELDPLWL TRQSLESLPS AMKPGCGWLP SSWLPDESLR RALRAASRDE SDALTDYATP
AGLPALRQQL AWRLAQHGVH AEPAQIMLAD SGTQALDFVC RLLLEPGDTV VLDDPCYFNF
QALLRAHRAR IVSVPYTPNG PDLARFEQTL VEHRPRLYIT NAALHNPTGA TLSPPVAHRL
LTLAADHGLL IVEDDIFADF ESTPAPRLAA FDGLQRVVSI GSFSKTLSAA IRCGYVAARP
EWIDALVDLK LATSFGHAQI GANVVHRLLV DGTYRRHLDG LRARLADAMG ETIRRLARAG
LAVWTEPRGG LFVWAQLPDG LDAARVARHA LDDDVVLAPG NVFSASHGAT SYLRFNVSRC
KEPAVFDALA RAMDAARAST AGARTAERHD TA
//
