ID B9BWH2_9BURK Unreviewed; 1008 AA.
AC B9BWH2;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Type III restriction enzyme, res subunit family {ECO:0000313|EMBL:EEE04989.1};
GN ORFNames=BURMUCGD2_3504 {ECO:0000313|EMBL:EEE04989.1};
OS Burkholderia multivorans CGD2.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=513052 {ECO:0000313|EMBL:EEE04989.1, ECO:0000313|Proteomes:UP000004535};
RN [1] {ECO:0000313|EMBL:EEE04989.1, ECO:0000313|Proteomes:UP000004535}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGD2 {ECO:0000313|EMBL:EEE04989.1,
RC ECO:0000313|Proteomes:UP000004535};
RX PubMed=23105085; DOI=10.1128/JB.01306-12;
RA Varga J.J., Losada L., Zelazny A.M., Brinkac L., Harkins D., Radune D.,
RA Hostetler J., Sampaio E.P., Ronning C.M., Nierman W.C., Greenberg D.E.,
RA Holland S.M., Goldberg J.B.;
RT "Draft Genome Sequence Determination for Cystic Fibrosis and Chronic
RT Granulomatous Disease Burkholderia multivorans Isolates.";
RL J. Bacteriol. 194:6356-6357(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEE04989.1}.
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DR EMBL; ACFC01000012; EEE04989.1; -; Genomic_DNA.
DR RefSeq; WP_006407279.1; NZ_ACFC01000012.1.
DR AlphaFoldDB; B9BWH2; -.
DR REBASE; 55538; Bmu2ORF3505P.
DR Proteomes; UP000004535; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0015668; F:type III site-specific deoxyribonuclease activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR045572; RE_endonuc_C.
DR PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR Pfam; PF19778; RE_endonuc; 1.
DR Pfam; PF04851; ResIII; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
FT DOMAIN 69..226
FT /note="Helicase/UvrB N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04851"
FT DOMAIN 885..984
FT /note="Type III restriction enzyme C-terminal endonuclease"
FT /evidence="ECO:0000259|Pfam:PF19778"
SQ SEQUENCE 1008 AA; 112316 MW; 9E7CAAB744030298 CRC64;
MRLHFEADLD YQRDAIDAVC DLFRGQESYR GDFSVLASAA PGTTAAAQGS LGFAMSERGV
GNRLSLTDDA LARNLADVQL RGGLPPSGSP GSRDFTVEME TGTGKTYVYL RTIFELNRRY
GFTKFVIVVP SIAIKEGVHK TLAITEDHFR ALYAGVPYDY FLYDSAKLGQ VRHFAASATI
QIMVMTVAAI NKKEVNNLYK DSEKTGGEKP IDLIRATRPI VIVDEPQSVD GGLEGRGREA
LSAMDPLCTL RYSATHVDRH HMVYRLDAVD AYERKLVKQI EIASAIVEDA HNKPYVRLVG
VSNRRGAISA RLELDVATAN GVKRQLVSAT DGDDLERLTK RALYAGLRIG EVHAAKGAEY
VELRHPEGET FLSLGEAFGD IDTLAVQREM IRRTIREHLD KELRLAERGV KVLSLFFVDS
VERYRRYDEN GMPVKGEYAL IFEEEYARAA RVPAYRALFD GVDIAREVER AHNGYFSIDR
KGGWTDTSES SAVARENAER AYGLIMREKE ALLSFDTPLK FIFSHSALKE GWDNPNVFQI
CTLRDIQTER ERRQTLGRGL RLAVDQDGER VRDPGVNTLT VIATERYESF AENLQKEIEA
DTGIRFGIVE QHQFAALPVQ EGDGPAHALG VELSRVLWMH LHEQGYVDAQ GKVLDRLKDA
LRQSALVLPD AFESLRAPIV AMLRKLSGRF AVRNADERRA IALRRDASGK AVVFGDDFRA
LWDRIRHRTV YRVDFDNAKL VRDCAAALRD APDIARARLQ WRKAEIDIGK SGVEAIEVGG
AGTVLIDEGE LPLPDLLTEL QDRTQLTRRS LATILADSGR LDDFRVNPQQ FIAVAADAIN
RYKRLALVAG IAYRKLGDRH VHALESFESE ALTGYLRNLR LEARKSIHEA VVCETDAERA
FADALEAHDG VKLYAKLPAW FRVATPLGSY HPDWAVLAEQ DGGERLYFVV DTPNADGDTP
TEHERAKLAC GEAHFRALAD GDDAARFVRV RHVDALFDGA AAPTRTAR
//
