ID B9DMK5_STACT Unreviewed; 238 AA.
AC B9DMK5;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Accessory gene regulator protein A {ECO:0000313|EMBL:CAL28454.1};
GN Name=agrA {ECO:0000313|EMBL:CAL28454.1};
GN OrderedLocusNames=Sca_1549 {ECO:0000313|EMBL:CAL28454.1};
OS Staphylococcus carnosus (strain TM300).
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=396513 {ECO:0000313|EMBL:CAL28454.1, ECO:0000313|Proteomes:UP000000444};
RN [1] {ECO:0000313|EMBL:CAL28454.1, ECO:0000313|Proteomes:UP000000444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TM300 {ECO:0000313|EMBL:CAL28454.1,
RC ECO:0000313|Proteomes:UP000000444};
RX PubMed=19060169; DOI=10.1128/AEM.01982-08;
RA Rosenstein R., Nerz C., Biswas L., Resch A., Raddatz G., Schuster S.C.,
RA Goetz F.;
RT "Genome analysis of the meat starter culture bacterium Staphylococcus
RT carnosus TM300.";
RL Appl. Environ. Microbiol. 75:811-822(2009).
CC -!- FUNCTION: Required for high-level post-exponential phase expression of
CC a series of secreted proteins. {ECO:0000256|ARBA:ARBA00037164}.
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DR EMBL; AM295250; CAL28454.1; -; Genomic_DNA.
DR RefSeq; WP_015900794.1; NC_012121.1.
DR AlphaFoldDB; B9DMK5; -.
DR GeneID; 60544743; -.
DR KEGG; sca:SCA_1549; -.
DR eggNOG; COG3279; Bacteria.
DR HOGENOM; CLU_000445_14_6_9; -.
DR OrthoDB; 9809318at2; -.
DR BioCyc; SCAR396513:SCA_RS07850-MONOMER; -.
DR Proteomes; UP000000444; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR CDD; cd17533; REC_LytTR_AgrA-like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 2.40.50.1020; LytTr DNA-binding domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR046947; LytR-like.
DR InterPro; IPR007492; LytTR_DNA-bd_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR37299:SF3; STAGE 0 SPORULATION PROTEIN A HOMOLOG; 1.
DR PANTHER; PTHR37299; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF04397; LytTR; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00850; LytTR; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR PROSITE; PS50930; HTH_LYTTR; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..125
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 143..238
FT /note="HTH LytTR-type"
FT /evidence="ECO:0000259|PROSITE:PS50930"
FT MOD_RES 59
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 238 AA; 27831 MW; C5CBC27AC04685FC CRC64;
MKIIICEDDQ QQRAHIEEII NNYTMIEEKP LEIALSTNDP YEVIEYAKNT NDICCYFLDI
QLDADINGIK LGSELRKFDT VGNIVFVTSY SELTYLTFVY KVAAMDFIFK DDPSEMKSRI
IDCIETALTR LQLLSKESNV ETIELKRGSN SVYVNYDDVM FFESSTKSHR LIAHLDNRQI
EFYGSLKELS NIDERFFRCH NSFVINLNNI EEVISKEREI HFKNGEHCYV SVRNLKKI
//
