ID B9DP42_STACT Unreviewed; 338 AA.
AC B9DP42;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Regulatory protein MsrR {ECO:0000256|ARBA:ARBA00040752};
GN OrderedLocusNames=Sca_1006 {ECO:0000313|EMBL:CAL27914.1};
OS Staphylococcus carnosus (strain TM300).
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=396513 {ECO:0000313|EMBL:CAL27914.1, ECO:0000313|Proteomes:UP000000444};
RN [1] {ECO:0000313|EMBL:CAL27914.1, ECO:0000313|Proteomes:UP000000444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TM300 {ECO:0000313|EMBL:CAL27914.1,
RC ECO:0000313|Proteomes:UP000000444};
RX PubMed=19060169; DOI=10.1128/AEM.01982-08;
RA Rosenstein R., Nerz C., Biswas L., Resch A., Raddatz G., Schuster S.C.,
RA Goetz F.;
RT "Genome analysis of the meat starter culture bacterium Staphylococcus
RT carnosus TM300.";
RL Appl. Environ. Microbiol. 75:811-822(2009).
CC -!- FUNCTION: Involved in SarA attenuation. Affects resistance to oxacillin
CC and teicoplanin, as well as the synthesis of virulence factors.
CC {ECO:0000256|ARBA:ARBA00037178}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004401};
CC Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004401}.
CC -!- SIMILARITY: Belongs to the LytR/CpsA/Psr (LCP) family.
CC {ECO:0000256|ARBA:ARBA00006068}.
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DR EMBL; AM295250; CAL27914.1; -; Genomic_DNA.
DR RefSeq; WP_015900255.1; NC_012121.1.
DR AlphaFoldDB; B9DP42; -.
DR GeneID; 60545303; -.
DR KEGG; sca:SCA_1006; -.
DR eggNOG; COG1316; Bacteria.
DR HOGENOM; CLU_016455_1_0_9; -.
DR OrthoDB; 9782542at2; -.
DR BioCyc; SCAR396513:SCA_RS05050-MONOMER; -.
DR Proteomes; UP000000444; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.630.190; LCP protein; 1.
DR InterPro; IPR004474; LytR_CpsA_psr.
DR NCBIfam; TIGR00350; lytR_cpsA_psr; 1.
DR PANTHER; PTHR33392; POLYISOPRENYL-TEICHOIC ACID--PEPTIDOGLYCAN TEICHOIC ACID TRANSFERASE TAGU; 1.
DR PANTHER; PTHR33392:SF8; REGULATORY PROTEIN MSRR; 1.
DR Pfam; PF03816; LytR_cpsA_psr; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 100..244
FT /note="Cell envelope-related transcriptional attenuator"
FT /evidence="ECO:0000259|Pfam:PF03816"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 338 AA; 38073 MW; 873FE2912330DB33 CRC64;
MTEEDKQKEN YKRSSNNPPP PRKKRMKKKI RKLPFILLGI LIILIAFIVY AVSGYKSGID
YAKKHNSNMK VQKFNGPVKN DGKISILLLG ADKSEGGKSR TDSIMVAQYD YIHKKMKIVS
VMRDTYAKIP GYRNYKINAA YSLGGPELLR KSLVENYGID PEYYAVIDFK GFEKMIDELA
PQGVPIDVEK DMSELIGVSL KKGHHNLNGK ELLGYARFRH DPEGDFGRVR RQQQVIKALK
QEMTKPGAIF KLPKVAGILR GYLNTDIPDS ALMQTGINFG IRGDKDVQTL TVPMKGTYQD
IQTAESGSAL EVDKPKNKKA IQEFLNDNSK KGNQQSKK
//
