ID B9EIZ9_MOUSE Unreviewed; 1003 AA.
AC B9EIZ9;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 22-FEB-2023, entry version 62.
DE SubName: Full=NLR family, pyrin domain containing 9B {ECO:0000313|EMBL:AAI41250.1};
GN Name=Nlrp9b {ECO:0000313|EMBL:AAI41250.1,
GN ECO:0000313|MGI:MGI:2675377};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAI41250.1};
RN [1] {ECO:0000313|EMBL:AAI41250.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain {ECO:0000313|EMBL:AAI41250.1};
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC141249; AAI41250.1; -; mRNA.
DR AlphaFoldDB; B9EIZ9; -.
DR PeptideAtlas; B9EIZ9; -.
DR AGR; MGI:2675377; -.
DR MGI; MGI:2675377; Nlrp9b.
DR CDD; cd08320; Pyrin_NALPs; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR004020; DAPIN.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR041075; NOD2_WH.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45690; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12; 1.
DR PANTHER; PTHR45690:SF13; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 9; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR Pfam; PF17779; NOD2_WH; 1.
DR Pfam; PF02758; PYRIN; 1.
DR SMART; SM00368; LRR_RI; 8.
DR SMART; SM01289; PYRIN; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50824; DAPIN; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 2: Evidence at transcript level;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614}.
FT DOMAIN 1..91
FT /note="Pyrin"
FT /evidence="ECO:0000259|PROSITE:PS50824"
FT DOMAIN 143..270
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
SQ SEQUENCE 1003 AA; 114790 MW; C23B63C75E0CDC91 CRC64;
MAGSSGYGLL KLLQKLSDEE FQRFKELLRE EPEKFKLKPI SWTKIENSSK ESLVTLLNTH
YPGQAWNMML SLFLQVNRED LSIMAQKKKR HKQTKYKKFM KTTFERIWTL ETNTHIPDRN
YHLIVEVQYK ALQEIFDSES EPVTAIVAGT TGEGKTTFLR KAMLDWASGV LLQNRFQYVF
FFSVFSLNNT TELSLAELIS STLPESSETV DDILSDPKRI LFILDGFDYL KFDLELRTNL
CNDWRKRLPT QIVLSSLLQK IMLPGCSLLL ELGQISVPKI RHLLKYPRVI TMQGFSERSV
EFYCMSFFDN QRGIEVAENL RNNEVLHLCS NPYLCWMFCS CLKWQFDREE EGYFKAKTDA
AFFTNFMVSA FKSTYAHSPS KQNRARLKTL CTLAVEGMWK ELFVFDSEDL RRNGISESDK
AVWLKMQFLQ THGNHTVFYH PTLQSYFAAM FYFLKQDKDI CVPVIGSIPQ LLGNMYARGQ
TQWLQLGTFL FGLINEQVAA LLQPCFGFIQ PIYVRQEIIC YFKCLGQQEC NEKLERSQTL
FSCLRDSQEE RFVRQVVDLL EEITVDISSS DVLSVTAYAL QKSSKLKKLH LHIQKTVFSE
IYCPDHCKTR TSIGKRRNTA EYWKTLCGIF CNLYVLDLDS CQFNKRAIQD LCNSMSPTPT
VPLTAFKLQS LSCSFMADFG DGSLFHTLLQ LPHLKYLNLY GTYLSMDVTE KLCAALRCSA
CRVEELLLGK CGISSKACGI IATSLINSKV KHLSLVENPL KNKGVMSLCE MLKDPSCVLQ
SLMLSYCCLT FIACGHLYEA LLSNKHLSLL DLGSNFLEDT GVNLLCEALK DPNCTLKELW
LPGCFLTSQC CEEISAVLIC NRNLKTLKLG NNNIQDTGVR QLCEALSHPN CNLECLGLDL
CEFTSDCCKD LALALTTCKT LNSLNLDWKT LDHSGLVVLC EALNHKRCNL KMLGLDKSAF
SEESQTLLQD VEKKNNNLNI LHHPWFEAER NKRGTRLVWN SRN
//
