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Database: UniProt
Entry: B9JZF7_AGRVS
LinkDB: B9JZF7_AGRVS
Original site: B9JZF7_AGRVS 
ID   B9JZF7_AGRVS            Unreviewed;       524 AA.
AC   B9JZF7;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   05-JUL-2017, entry version 73.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:ACM35269.1};
GN   OrderedLocusNames=Avi_0391 {ECO:0000313|EMBL:ACM35269.1};
OS   Agrobacterium vitis (strain S4 / ATCC BAA-846) (Rhizobium vitis
OS   (strain S4)).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium.
OX   NCBI_TaxID=311402 {ECO:0000313|EMBL:ACM35269.1, ECO:0000313|Proteomes:UP000001596};
RN   [1] {ECO:0000313|EMBL:ACM35269.1, ECO:0000313|Proteomes:UP000001596}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S4 / ATCC BAA-846 {ECO:0000313|Proteomes:UP000001596};
RX   PubMed=19251847; DOI=10.1128/JB.01779-08;
RA   Slater S.C., Goldman B.S., Goodner B., Setubal J.C., Farrand S.K.,
RA   Nester E.W., Burr T.J., Banta L., Dickerman A.W., Paulsen I.,
RA   Otten L., Suen G., Welch R., Almeida N.F., Arnold F., Burton O.T.,
RA   Du Z., Ewing A., Godsy E., Heisel S., Houmiel K.L., Jhaveri J., Lu J.,
RA   Miller N.M., Norton S., Chen Q., Phoolcharoen W., Ohlin V.,
RA   Ondrusek D., Pride N., Stricklin S.L., Sun J., Wheeler C., Wilson L.,
RA   Zhu H., Wood D.W.;
RT   "Genome sequences of three Agrobacterium biovars help elucidate the
RT   evolution of multichromosome genomes in bacteria.";
RL   J. Bacteriol. 191:2501-2511(2009).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP000633; ACM35269.1; -; Genomic_DNA.
DR   RefSeq; WP_012654799.1; NC_011989.1.
DR   STRING; 311402.Avi_0391; -.
DR   EnsemblBacteria; ACM35269; ACM35269; Avi_0391.
DR   GeneID; 31494057; -.
DR   KEGG; avi:Avi_0391; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235660; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001596; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001596};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001596}.
FT   DOMAIN      217    345       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      432    501       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     225    232       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   524 AA;  58148 MW;  063F973707A36B03 CRC64;
     MQMKMVTASA AASGDEARTI DQAVSPDATG GPNAVVDDTV AGDEVRYDAL FERFSARLRA
     QVGPDVFASW FGRLKLHSSS KSVIRLSVPT TFLKSWINNR YLDLITSIFQ AEDASILKIE
     ILVRSASRNS RAPVVEDRAV EPSLSSSQKR QAPQSIGQMA PAIANAAAPQ RAPVQGPLFG
     SPLDSRYTFD GFVEGASNRV AVAAAKTIAE AGAGAVRFNP LFIHSSVGLG KTHLLQAIAN
     AAIHSPRAPR VVYLTAEYFM WRFATAIRDN DALTLKDSLR NIDLLIIDDM QFLQGKTIQH
     EFCHLLNMLL DSAKQVVVAA DRAPWELESL DQRVRSRLQG GVAIEMEAPD YDMRLDMLKT
     RLALAKKEDP SLEIPAEIIA HVARNVASSG RDLEGAFNQL LFRRSFEANM TIERVDELLA
     HLVGAAEQKR VRIEDIQRVV ARHYNVSRQE LVSNRRTRVI VKPRQIAMYL SKTLTPRSFP
     EIGRRFGGRD HTTVLHAVRK IEELISGDQK LSQEIELLRR LINE
//
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