ID B9L3H8_THERP Unreviewed; 342 AA.
AC B9L3H8;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Aldolase {ECO:0000313|EMBL:ACM06757.1};
GN OrderedLocusNames=trd_A0342 {ECO:0000313|EMBL:ACM06757.1};
OS Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2).
OG Plasmid Tros {ECO:0000313|Proteomes:UP000000447}.
OC Bacteria; Thermomicrobiota; Thermomicrobia; Thermomicrobiales;
OC Thermomicrobiaceae; Thermomicrobium.
OX NCBI_TaxID=309801 {ECO:0000313|EMBL:ACM06757.1, ECO:0000313|Proteomes:UP000000447};
RN [1] {ECO:0000313|EMBL:ACM06757.1, ECO:0000313|Proteomes:UP000000447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27502 / DSM 5159 / P-2
RC {ECO:0000313|Proteomes:UP000000447};
RC PLASMID=Tros {ECO:0000313|Proteomes:UP000000447};
RX PubMed=19148287; DOI=10.1371/journal.pone.0004207;
RA Wu D., Raymond J., Wu M., Chatterji S., Ren Q., Graham J.E., Bryant D.A.,
RA Robb F., Colman A., Tallon L.J., Badger J.H., Madupu R., Ward N.L.,
RA Eisen J.A.;
RT "Complete genome sequence of the aerobic CO-oxidizing thermophile
RT Thermomicrobium roseum.";
RL PLoS ONE 4:E4207-E4207(2009).
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
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DR EMBL; CP001276; ACM06757.1; -; Genomic_DNA.
DR RefSeq; WP_012642744.1; NC_011961.1.
DR AlphaFoldDB; B9L3H8; -.
DR KEGG; tro:trd_A0342; -.
DR eggNOG; COG0329; Bacteria.
DR HOGENOM; CLU_846989_0_0_0; -.
DR OrthoDB; 9778880at2; -.
DR Proteomes; UP000000447; Plasmid Tros.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF51; BLL4205 PROTEIN; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Plasmid {ECO:0000313|EMBL:ACM06757.1}.
FT ACT_SITE 153
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 181
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
SQ SEQUENCE 342 AA; 38591 MW; F91F5796D549DC58 CRC64;
MAFPRIGASD LRGIMAYPPT PAKPNAGDID ARDTVDLDET ERMIKQLLQD GVDSIATNGT
LGEMATLTLE EWKAFASVVV ETVRAHDPDF PLFIGATTLN TRDTIDRMRF LRDIGAPGVL
LGRPMWSEMT AKTMIRFYQD VAEAVPDLAI CVYDNTAAFR GIIPTEVYEA LSRIPQVVAV
KYAGGAAIGF RYHNDLQAVG DRIKLFPIEC IWFFAYSLYG ERVPGCWSTT ATCGPEPVLY
LRDVLLANDL TEGRWIAERI LWAHEPFIVS RDFPEFARYN IQLERLRYEA AGYIKPGPSR
PPYYMDLLPE QHVESTLEHV RRWQQVRQEV AERLKARAAT TA
//
