ID B9LQA3_HALLT Unreviewed; 734 AA.
AC B9LQA3;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=PAS/PAC sensor signal transduction histidine kinase {ECO:0000313|EMBL:ACM57524.1};
GN OrderedLocusNames=Hlac_1946 {ECO:0000313|EMBL:ACM57524.1};
OS Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM
OS 34).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum.
OX NCBI_TaxID=416348 {ECO:0000313|EMBL:ACM57524.1, ECO:0000313|Proteomes:UP000000740};
RN [1] {ECO:0000313|EMBL:ACM57524.1, ECO:0000313|Proteomes:UP000000740}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34
RC {ECO:0000313|Proteomes:UP000000740};
RX PubMed=27617060; DOI=10.1186/s40793-016-0194-2;
RA Anderson I.J., DasSarma P., Lucas S., Copeland A., Lapidus A.,
RA Del Rio T.G., Tice H., Dalin E., Bruce D.C., Goodwin L., Pitluck S.,
RA Sims D., Brettin T.S., Detter J.C., Han C.S., Larimer F., Hauser L.,
RA Land M., Ivanova N., Richardson P., Cavicchioli R., DasSarma S.,
RA Woese C.R., Kyrpides N.C.;
RT "Complete genome sequence of the Antarctic Halorubrum lacusprofundi type
RT strain ACAM 34.";
RL Stand. Genomic Sci. 11:70-70(2016).
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DR EMBL; CP001365; ACM57524.1; -; Genomic_DNA.
DR RefSeq; WP_015910649.1; NC_012029.1.
DR AlphaFoldDB; B9LQA3; -.
DR GeneID; 7399898; -.
DR KEGG; hla:Hlac_1946; -.
DR eggNOG; arCOG02365; Archaea.
DR eggNOG; arCOG06712; Archaea.
DR HOGENOM; CLU_000445_114_58_2; -.
DR Proteomes; UP000000740; Chromosome 1.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00130; PAS; 4.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 4.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08448; PAS_4; 3.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 4.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 4.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ACM57524.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000740};
KW Transferase {ECO:0000313|EMBL:ACM57524.1}.
FT DOMAIN 13..64
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 136..182
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 207..261
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 258..328
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 329..384
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 381..451
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 512..733
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 734 AA; 80617 MW; ABDD2E3133B72A73 CRC64;
MSRGNDDEPS PPDGGFFSSV VEESRDPIVS IDDAGAIVYA NPAAEDALGR DAASLADRRL
AELIPDATTN RRAASLRDRL VEPARLDDAG DVSVPLAAAD GETRTFSVRF HAHDVDGKPV
YTGVFRERSS GDRDREFRTF RNLVEHAGHA IYVTDTDGTI EYVNPAFTRH TGYEPEQVIG
ETPAVLNSGE MSDEYFVSLW ETLCAGEVWE EEIVDRRKDG THYHAHQTIA PVFDDAGTVS
RFVAIQTDVT ERKAAEGKLK QYRDIVERLD DPIMLQNRDG EFELLNEAVS EFAGTSREEL
YDDDETAFMD TETAAEIDER RQEVLRTEEP VEYEVSPSFE RSGRDATFST RRYPYYDGAE
ALAGTFAICR DVTEIKEREA DLELYERAVD GATDLIAAVD RDERFLFANE QYRTYHGIGD
ADITGLTLAD AVGDDSYPDV RRQMTRALAG QSVEYRAMRR HPVRGTRMFD VLYYPLEGPD
KEDNRVVGVV GVLRDVTDSE NRAHQLRVVD RVLQHNLRNA MTVVRGRAQQ IADTAGEREA
AADEGAAAGD VDSVAAGAAD IAARAEALLS TSEKVHQITE VLSDPPETEP VDVARAVEAV
AAEIADAFPE ASVTVSTPDG TVHASATTWI DWAIDELVRN AIVHHDRESP TVEITVTAAE
DTVTVTITDD GPGLTGMNRD VLETGEAVDA LYHGSGLGLW LVYWVVQQSG GDAAVRDATP
RGTVVTVTLP RSDR
//
