ID B9PYX4_TOXGV Unreviewed; 514 AA.
AC B9PYX4; A0A0F7UPZ2; B9QHH4; S7VZQ5;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Serine/threonine-protein phosphatase PGAM5, mitochondrial {ECO:0000256|ARBA:ARBA00039765};
DE AltName: Full=Serine/threonine-protein phosphatase Pgam5, mitochondrial {ECO:0000256|ARBA:ARBA00040722};
GN ORFNames=BN1205_053330 {ECO:0000313|EMBL:CEL71979.1}, TGVEG_222910
GN {ECO:0000313|EMBL:ESS29996.1};
OS Toxoplasma gondii (strain ATCC 50861 / VEG).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS29996.1, ECO:0000313|Proteomes:UP000002226};
RN [1] {ECO:0000313|EMBL:ESS29996.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS29996.1};
RA Paulsen I.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT "Annotation of Toxoplasma gondii VEG.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ESS29996.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS29996.1};
RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., Brunk B.,
RA Roos D., Caler E., Lorenzi H.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CEL71979.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:CEL71979.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
CC -!- SIMILARITY: Belongs to the phosphoglycerate mutase family. BPG-
CC dependent PGAM subfamily. {ECO:0000256|ARBA:ARBA00006717}.
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DR EMBL; LN714491; CEL71979.1; -; Genomic_DNA.
DR EMBL; AAYL02000269; ESS29996.1; -; Genomic_DNA.
DR AlphaFoldDB; B9PYX4; -.
DR SMR; B9PYX4; -.
DR STRING; 432359.B9PYX4; -.
DR SwissPalm; B9PYX4; -.
DR PaxDb; 5811-TGME49_022910; -.
DR EnsemblProtists; ESS29996; ESS29996; TGVEG_222910.
DR VEuPathDB; ToxoDB:TGVEG_222910; -.
DR eggNOG; KOG4609; Eukaryota.
DR OMA; VIRYMLM; -.
DR Proteomes; UP000002226; Partially assembled WGS sequence.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-KW.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR PANTHER; PTHR20935; PHOSPHOGLYCERATE MUTASE-RELATED; 1.
DR PANTHER; PTHR20935:SF0; SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL; 1.
DR Pfam; PF00300; His_Phos_1; 2.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002226}.
FT REGION 122..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..195
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 514 AA; 55889 MW; 6E2DC18C7F5C18C5 CRC64;
MSSLRNAGKG RVLSSALRVF NFLEPPERVS LLGPTRAVIP LQRASVHRLW KSSPAKSPPS
LREFATSCSH VLSVKRGVCP IPQGGRPLTR GSLAPYRIAG TPLLLLQPRP SFFAFRSFVS
ETKVPSPTSK PSSPDETSQA AEEASSSTCE ATQKAASSTE KTYEPQGQSG SDTVPHSTFR
LRAGEESDPR RTDSGEQGSS DQLPPPGRGL PLLFAILTAL SGVAIGLILY DAVVGETALL
SGAWKFDWDG PWLQAATQRE AQLAAQGVQT HPPAAVRAVE AGVHVRPPTR QIILVRHGQY
ANVVSTNDEE QGLTELGKLQ AAITGRRLKE LLKDQHVVAI WHSDMKRARE TAEIIHKEAF
PDRPLLQDPL LAEGVPAEPV PPSRTFKPTQ EEIMVDSARI EEAFRRYFYR ALPPTSPAPT
AAQVAASPSA DSEKQTGVTA ECNVGNDSYI ILVCHGNVIR YMLMRALQLP GCAWLRWATY
NTGISWISID SKGYVSCREF GDVGHLQADM ITYH
//
