ID B9QFL0_TOXGV Unreviewed; 269 AA.
AC B9QFL0; A0A0F7UYZ1;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=3'-5' exoribonuclease csl4, putative {ECO:0000313|EMBL:CEL73793.1};
DE SubName: Full=Putative 3'-5' exoribonuclease csl4 {ECO:0000313|EMBL:ESS33081.1};
GN ORFNames=BN1205_045800 {ECO:0000313|EMBL:CEL73793.1}, TGVEG_203610
GN {ECO:0000313|EMBL:ESS33081.1};
OS Toxoplasma gondii (strain ATCC 50861 / VEG).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS33081.1, ECO:0000313|Proteomes:UP000002226};
RN [1] {ECO:0000313|EMBL:ESS33081.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS33081.1};
RA Paulsen I.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT "Annotation of Toxoplasma gondii VEG.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ESS33081.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS33081.1};
RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., Brunk B.,
RA Roos D., Caler E., Lorenzi H.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CEL73793.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:CEL73793.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
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DR EMBL; LN714496; CEL73793.1; -; Genomic_DNA.
DR EMBL; AAYL02000117; ESS33081.1; -; Genomic_DNA.
DR AlphaFoldDB; B9QFL0; -.
DR STRING; 432359.B9QFL0; -.
DR PaxDb; 5811-TGME49_003610; -.
DR EnsemblProtists; ESS33081; ESS33081; TGVEG_203610.
DR VEuPathDB; ToxoDB:TGVEG_203610; -.
DR eggNOG; KOG3409; Eukaryota.
DR OMA; YYCSTAR; -.
DR Proteomes; UP000002226; Partially assembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR039771; Csl4.
DR InterPro; IPR019495; EXOSC1_C.
DR InterPro; IPR025721; Exosome_cplx_N_dom.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR PANTHER; PTHR12686; 3'-5' EXORIBONUCLEASE CSL4-RELATED; 1.
DR PANTHER; PTHR12686:SF8; EXOSOME COMPLEX COMPONENT CSL4; 1.
DR Pfam; PF14382; ECR1_N; 1.
DR Pfam; PF10447; EXOSC1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF110324; Ribosomal L27 protein-like; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Exosome {ECO:0000256|ARBA:ARBA00022835};
KW Reference proteome {ECO:0000313|Proteomes:UP000002226}.
FT DOMAIN 69..104
FT /note="Exosome complex component N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14382"
FT DOMAIN 173..213
FT /note="Exosome complex component CSL4 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF10447"
FT REGION 1..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 103..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 269 AA; 28413 MW; A864BEF83689005F CRC64;
MEANVPSLQH SGMPLLPPGL QGRNSQQGSL LSARGSGTVA PENPTWEGTS AGRVQASPAK
PVSSRSVRTP GERLSSTSEY ACGRGTYVKD DFIYAAVVGI EQIDHPTPRG QPTTTEGRGG
QKRAGGLPVL SVVPFAKSAS VLPTTGCFVL AQVTKVARHR VECSILAVDG HTLAEPFRGF
IRSQDIRETD VDSVDVLECF KPGDVVRAKV ISMGDGRCYV LSTASAELGV LFAQGKEGGQ
LQPVTCTLMR CDITGRLQKR KVAAPVLLS
//
