ID B9RG81_RICCO Unreviewed; 1005 AA.
AC B9RG81;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 61.
DE SubName: Full=Glutamate receptor 2 plant, putative {ECO:0000313|EMBL:EEF49536.1};
GN ORFNames=RCOM_1452030 {ECO:0000313|EMBL:EEF49536.1};
OS Ricinus communis (Castor bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC Ricinus.
OX NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN [1] {ECO:0000313|Proteomes:UP000008311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX PubMed=20729833; DOI=10.1038/nbt.1674;
RA Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA Rabinowicz P.D.;
RT "Draft genome sequence of the oilseed species Ricinus communis.";
RL Nat. Biotechnol. 28:951-956(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
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DR EMBL; EQ973778; EEF49536.1; -; Genomic_DNA.
DR AlphaFoldDB; B9RG81; -.
DR STRING; 3988.B9RG81; -.
DR eggNOG; KOG1052; Eukaryota.
DR InParanoid; B9RG81; -.
DR Proteomes; UP000008311; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 3.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR18966:SF523; GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:EEF49536.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008311};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..1005
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002890773"
FT TRANSMEM 596..616
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 658..682
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 855..879
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 467..834
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 428..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 950..971
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..447
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 955..971
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 766..838
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 1005 AA; 110728 MW; 0A910DE8C36C82DC CRC64;
MMRKNTCTGL VLSFTFLASW SMPLTESVMA QNTKVSVDVG VILDYDRWVG RIGLSCINMS
LSDFYATHSH FKTRLLLHTR DSKEDVVGAA AAALDLIKNV EVEAIIGPST SMQANFVIDL
GQKAQVPIIS FSASSPSLAA IRSPYFFRAT RSDSCQVNAI GAIVQAFGWK AAVPIYVDND
YGVGVIPYLT DTLQEVDARV PYRSAISPFA TDDQIIEELY KLKAMQTRVF ILHMLPAIGI
RLITIAKEIG MMSTGYVWIM TDGMTDFLDS LDNLDIELMQ GVLGVKPYVP RTKKIERFRT
QWKKKFHHDH PDIIDSELNV YGLWAYDVTA ALAMAIEKVA ANTTNFGFRK ANVSGNGSTD
LETFGVSRIG PDLQRALSKT QFEGITGDFH LIDGQLQSSV IQIVNVNGDG VRRVGFWLPG
KGLVKRMKSS TEKGSNPPSN TSLSTVIWPG DTASVPKGWE IPRNGKKLRI GVPVKEGFTQ
FVNVTRNPAT NTSRVEGYCI DLFDAVVSEL PYAVTYEYIP FADSEGKSAG PYNSLIDQVY
LGNYDAAVGD ISIVANRSSY IDFTLPYMES GRMTMIVPIT DDYSRKAWVF LKPLTWDLWV
ATLCLFFFIA FVVWVLEHRI NEDFRGPPSQ QVSTSFWFSV STMVFAHGER VVSNSARVVV
IIWCFVGLIL TQSYTASLSS FLTIQQLQPS VTTLDELIRK GENVGYQQGA FVRTTLKSMG
FDDSKLVPYK SAEECDQLLS KGIKNGGIAA AFEEPTSIHL ILAQNCSKYT LVEPTSMLKT
TRWKSTSNIE KLNTDGLGFV FPKGSPLAPD ISRAILKVTQ GEKIREIEGR WFGTKATCPD
RSSSAPLNRL GLNSFWGLFL IAGIVSFFAL IIYIATFIYQ NKEVWMPSDS GVVPTWRRRF
LDLLNLFKDA VNDESGITLP VIGEPIRSTR FPAVSAGDKA KNIKAAIIPT GKNRSSKGGG
GSGGSSKGNT TIDAARTAST ATLTKPKHRT IVLSVPILVI LLEKL
//
