ID   B9RT78_RICCO            Unreviewed;      1357 AA.
AC   B9RT78;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   24-JAN-2024, entry version 51.
DE   RecName: Full=Fanconi anemia group I protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=RCOM_0681730 {ECO:0000313|EMBL:EEF45561.1};
OS   Ricinus communis (Castor bean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC   Ricinus.
OX   NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN   [1] {ECO:0000313|Proteomes:UP000008311}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX   PubMed=20729833; DOI=10.1038/nbt.1674;
RA   Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA   Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA   Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA   Rabinowicz P.D.;
RT   "Draft genome sequence of the oilseed species Ricinus communis.";
RL   Nat. Biotechnol. 28:951-956(2010).
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DR   EMBL; EQ973812; EEF45561.1; -; Genomic_DNA.
DR   STRING; 3988.B9RT78; -.
DR   eggNOG; KOG4553; Eukaryota.
DR   InParanoid; B9RT78; -.
DR   Proteomes; UP000008311; Unassembled WGS sequence.
DR   GO; GO:0070182; F:DNA polymerase binding; IBA:GO_Central.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR026171; FANCI.
DR   InterPro; IPR029310; FANCI_HD1.
DR   InterPro; IPR029312; FANCI_HD2.
DR   InterPro; IPR029308; FANCI_S1.
DR   InterPro; IPR029315; FANCI_S2.
DR   InterPro; IPR029314; FANCI_S4.
DR   PANTHER; PTHR21818; BC025462 PROTEIN; 1.
DR   PANTHER; PTHR21818:SF0; FANCONI ANEMIA GROUP I PROTEIN; 1.
DR   Pfam; PF14679; FANCI_HD1; 1.
DR   Pfam; PF14680; FANCI_HD2; 1.
DR   Pfam; PF14675; FANCI_S1; 1.
DR   Pfam; PF14676; FANCI_S2; 1.
DR   Pfam; PF14678; FANCI_S4; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008311}.
FT   DOMAIN          119..280
FT                   /note="FANCI solenoid 1"
FT                   /evidence="ECO:0000259|Pfam:PF14675"
FT   DOMAIN          284..365
FT                   /note="FANCI helical"
FT                   /evidence="ECO:0000259|Pfam:PF14679"
FT   DOMAIN          378..533
FT                   /note="FANCI solenoid 2"
FT                   /evidence="ECO:0000259|Pfam:PF14676"
FT   DOMAIN          550..626
FT                   /note="FANCI helical"
FT                   /evidence="ECO:0000259|Pfam:PF14680"
FT   DOMAIN          1036..1275
FT                   /note="FANCI solenoid 4"
FT                   /evidence="ECO:0000259|Pfam:PF14678"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1270..1357
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1270..1324
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1335..1351
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1357 AA;  152226 MW;  7DE8E339AB1ED2A1 CRC64;
     MATATTATTS GRDQNLPPPP LTDTEIINLA YKNHLHPYIL STSSIPTLIS YLKTRSHSSV
     ALTDYTLSLL SLISLSPHNP SLSSLLSSLL STYTNLFLSL IIPRDSNSLK TINLFTTLLT
     YIPVNDLDSI ADSILNHLSS LVTSEDTQIL EIIPGCLSCL YSEKGKDSVN LILDKIIEIQ
     WSKVLLIKMV SLGREFLQFL DKMRARVFLE NVFNGMKGVD LQDLPSLAYQ LLVLASKGFN
     KREVIEGILR FFGSDLGSKG SSIVRQIEGT VLLHVNFAVK QDPSLGQEVI RLVKLGCRAL
     NHFTVSILLS IARVRRFKEN SIGVLKTAVL SAYRDYKFSS DIMWLADDLK EEYLQNVQVL
     EKAILRAVNE SNCGREHIVP TVVQFSFVLL ESLEGGNHRD LCNFNGLLGV EALSVQMLKT
     LFEVHDMARN EIIEQCKFRI LSVRPEQSTP IIRLLAFLVR SCPYPMLEHV SRLKELLDYF
     TFMNGNVASD LVTALVPLIK FNRDLRDYTI LVVRKAMFRQ EDAVRLAATN AIVSVILAEK
     QSNRDGFSFQ DSSSQAGCSQ PAEIPSGHGG GLFRELSGLL QRCLYQKAKV KEVMYHGLLK
     LVLVDPASAA AVFDFLWPHF LRFFKEFIIS YVKFGKGKLM DFNFKCNIVP ELAGRSLSGE
     SFSKAFLKIR DFLKKGNLED IPSPTSDEEQ GKCHALLLSG LIEVVLNSIA SELETATGLK
     RINLQKEILE IVNFHSTLKK YTSARQSCGV KRGSQQATTL DVPGNSFFSN NTMTQEQIPF
     LATSSLCQLM KTTLDLCNNE WFKGSTASQN HSQSSSSGTL KCFKIVPFVL NSSLHHIRSY
     ATGRKEDPIK NLIYGEIKLM APPLLKLICL LNSGPKFATD HKKEMKGKND FEDRKEHLHL
     ALLCLKELIA ISLKNSNSSG LLEDLLSVST LEYELDEEFE EASRIDDHQI RIKVLLIVKI
     LRPLFAELLA QSSFNEIEIL CDIMLMVGDK LPSKWRNSSG SWGINVCKSH GIRNSKVARS
     VAALAISLSS PDDLIVAHDM SKELLDVTGF IGPESNKPLE ISESCPIINQ STSTAISSCI
     LKLIEAVIND MDWTIKKLKT FFLIEQRYIH VSQSGEHAPG LTVEDNLYLR AEAVVKVLSF
     FVLMNLKDPQ AEHLLRLIAK FYKHLAQISR LRIATKGCKQ LLPTPTFQRL VEVTCKKLTV
     PLYKFVAEIQ RVQQEKPNTK GIINKIKREN KCIPELIFQI EDYEKYLIRL SKASKVNLLK
     HAKRSTSRDF RILDPPNDKE EADLNHEHNN DDAVGANVDR SHEDSEDNVS DKFSSRRKDS
     PEIAEESESE GEDGCGLPNG KRMRRDRVVQ DTDDDEA
//