ID   B9RUW1_RICCO            Unreviewed;      1066 AA.
AC   B9RUW1;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   SubName: Full=Disease resistance protein RPS5, putative {ECO:0000313|EMBL:EEF44694.1};
DE            EC=3.1.3.16 {ECO:0000313|EMBL:EEF44694.1};
GN   ORFNames=RCOM_0895260 {ECO:0000313|EMBL:EEF44694.1};
OS   Ricinus communis (Castor bean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC   Ricinus.
OX   NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN   [1] {ECO:0000313|Proteomes:UP000008311}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX   PubMed=20729833; DOI=10.1038/nbt.1674;
RA   Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA   Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA   Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA   Rabinowicz P.D.;
RT   "Draft genome sequence of the oilseed species Ricinus communis.";
RL   Nat. Biotechnol. 28:951-956(2010).
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
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DR   EMBL; EQ973818; EEF44694.1; -; Genomic_DNA.
DR   AlphaFoldDB; B9RUW1; -.
DR   STRING; 3988.B9RUW1; -.
DR   eggNOG; KOG4658; Eukaryota.
DR   InParanoid; B9RUW1; -.
DR   Proteomes; UP000008311; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR   CDD; cd06222; RNase_H_like; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR044730; RNase_H-like_dom_plant.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR33463:SF190; NB-ARC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR33463; NB-ARC DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF13855; LRR_8; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000313|EMBL:EEF44694.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008311};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        1033..1052
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          170..316
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   COILED          25..59
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1066 AA;  121412 MW;  C6E4023D49CA9A87 CRC64;
     MELVSPILDI GRCLWQSAST RAAFLLHLEK NSDSLEIAID QLKNLRDDVI TRVEEQEDKQ
     QMERTKRVSD WLAKVEQMEA QVTKVLQQGK EVVGKKCLLF CCPRNCRASY KLGKKVSKMI
     GEVDKLKKPG DFDVLAYRLP RAPVDEMPME KTVGLDSMFE KVWRSIEDKS SGIIGLYGLG
     GVGKTTLLKK INNQFSNTTH DFDVVIWVAV SKQINVENIQ EVIRNKLEIG NSIWINRSDE
     LERAIEIYRV LRRKKFVLLL DDVWERLDLS KVGVPFPGNN NESRVIFTTR SEEVCGYMEA
     DRRFRVECLA EQDALNLFQK MVGEDTLSSH QEIPQLAQIV AKKCQGLPLA LITTGRAMAS
     RKKPQEWKYA MKALQSYPSK FSGMEDHVFP ILKFSYDSLN DETVKTCFLY CSLFPEDHII
     LKEELINLWI GEGFLDKFDD IHDARIEGEY IIGSLKLAGL LEGDELEEHL GVSTECVWLH
     DVIRDMALWL ACEHGKETKI LVRDQPGRIN LDQNQVKEVE KISMWSHHVN VIEGFLIFPN
     LQTLILRNSR LISIPSEVIL CVPGLKVLDL SSNHGLAELP EGIGKLINLH YLNLSWTAIK
     EMSTEIKKLT KLRCLVLDNT KYLQLIAKEV ISSLISLQRF SKLATIDFLY NEFLNEVALL
     DELQSLKNLN DLSINLSTSD SVEKFFNSPI LQGCIRELTL VECSEMTSLD ISLSSMTRMK
     HLEKLELRFC QSISELRVRP CLIRKANPSF SSLRFLHIGL CPIRDLTWLI YAPKLETLEL
     VNCDSVNEVI NANCGNVKVE ADHNIFSNLT KLYLVKLPNL HCIFHRALSF PSLEKMHVSE
     CPKLRKLPFD SNSNNTLNVI KGERSWWDGL QWDNEGLKDL LSSKFVEEYY TITDSLISYL
     REELPMLCNI LNLPLLVAQV TPFFSSNQSC GGINSLGSIS WFKPPQGWLI VNADAATFGR
     ENRTGWGMIA RDGSGYFIAA RALSLDGCFE VRDAEAMGVR EALSWANQMG WNAVVLEMEH
     WWFFGPYSSI KELILPAMVW SLMIVYILFL ILKTLGSPLC GILQTV
//