ID   B9RYD1_RICCO            Unreviewed;      1094 AA.
AC   B9RYD1;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 67.
DE   SubName: Full=Leucine-rich repeat-containing protein, putative {ECO:0000313|EMBL:EEF43640.1};
GN   ORFNames=RCOM_0812250 {ECO:0000313|EMBL:EEF43640.1};
OS   Ricinus communis (Castor bean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC   Ricinus.
OX   NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN   [1] {ECO:0000313|Proteomes:UP000008311}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX   PubMed=20729833; DOI=10.1038/nbt.1674;
RA   Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA   Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA   Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA   Rabinowicz P.D.;
RT   "Draft genome sequence of the oilseed species Ricinus communis.";
RL   Nat. Biotechnol. 28:951-956(2010).
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DR   EMBL; EQ973830; EEF43640.1; -; Genomic_DNA.
DR   RefSeq; XP_002518715.1; XM_002518669.2.
DR   AlphaFoldDB; B9RYD1; -.
DR   GeneID; 8288154; -.
DR   KEGG; rcu:8288154; -.
DR   eggNOG; ENOG502SI7S; Eukaryota.
DR   InParanoid; B9RYD1; -.
DR   OrthoDB; 517237at2759; -.
DR   Proteomes; UP000008311; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd00009; AAA; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR011713; Leu-rich_rpt_3.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR11017:SF564; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE; 1.
DR   PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR   Pfam; PF07725; LRR_3; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF01582; TIR; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008311}.
FT   DOMAIN          21..187
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   1094 AA;  125473 MW;  D44C1BC5046DF3E4 CRC64;
     MNFSSSSASA SSSSSSTTSQ EKYDVFLSFR GEDTRYNFTS HLHAALNGKK IPTFIDDDLE
     RGNEISPSLL KAIEESKISV VIISQDYPSS KWCLEELVKI LECMKNRGQM VIPVFYRVDP
     SHVRNQTGSF EDVFARHEES LSVSKEKVQS WRAALKEVAN LSGWHSTSTR PEAEAVKEII
     EVIVKKLNQM SPNCYSRGLV GMESRIQEIE SLLCLRSSNV RIVGIWGMGG LGKTTLARAI
     YDRIAPQFEI CYFLSNAREQ LQRCTLSELQ NQLFSTLLEE QSTLNLQRSF IKDRLCRKKV
     LIVIDDADDS TQLQELLLES EPDYFGSGSR IIITSRDKQV LRNIARDKIY AMQKLKKHEA
     LQLFSLKAFK QDNPTCRHCR LQAERVVKYA KGNPLALTVL GSALFGKREK DWKSALERLE
     RNPNKKIDDV LRISYDGLDS EERSIFLDIA CFFRGQDRDF VTKTLDGYYG SAHSVISTLI
     DRSVIMLSSD SSKLDLHDLL QEMGRKIVFE ESKNPENRSR LWTPEDVCYV LNENRGTEAI
     EGISLDKSKA TSEIRLKPDA FSRMCRLRFL KFYKSPGDFY RSPGDRHSKD KLQISRDGLQ
     SLPNELRHLY WIDFPMKSLP PSFNPENLVV LHLRNSKVKK LWTGTQNLVK LKEIDLSGSK
     YLIGIPDLSK AIYIEKIDLS DCDNLEEVHS SIQYLNKLEF LNLWHCNKLR RLPRRIDSKV
     LKVLKLGSTR VKRCPEFQGN QLEDVFLYCP AIKNVTLTVL SILNSSRLVH LFVYRCRRLS
     ILPSSFYKLK SLKSLDLLHC SKLESFPEIL EPMYNIFKID MSYCRNLKSF PNSISNLISL
     TYLNLAGTAI KQMPSSIEHL SQLDFLDLKD CKYLDSLPVS IRELPQLEEM YLTSCESLHS
     LPELPSSLKK LRAENCKSLE RVTSYKNLGE ATFANCLRLD QKSFQITDLR VPECIYKERY
     LLYPGSEVPG CFSSQSMGSS VTMQSSLNEK LFKDAAFCVV FEFKKSSDCV FEVRYREDNP
     EGRIRSGFPY SETPILTNTD HVLIWWDECI DLNNISGVVH SFDFYPVTHP KTGQKEIVKH
     CKVKRCGLHM LPRT
//