ID   B9SDH1_RICCO            Unreviewed;       516 AA.
AC   B9SDH1;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=Cytochrome P450, putative {ECO:0000313|EMBL:EEF38408.1};
DE            EC=1.14.14.1 {ECO:0000313|EMBL:EEF38408.1};
GN   ORFNames=RCOM_1517780 {ECO:0000313|EMBL:EEF38408.1};
OS   Ricinus communis (Castor bean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC   Ricinus.
OX   NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN   [1] {ECO:0000313|Proteomes:UP000008311}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX   PubMed=20729833; DOI=10.1038/nbt.1674;
RA   Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA   Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA   Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA   Rabinowicz P.D.;
RT   "Draft genome sequence of the oilseed species Ricinus communis.";
RL   Nat. Biotechnol. 28:951-956(2010).
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|ARBA:ARBA00001971};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR   EMBL; EQ973927; EEF38408.1; -; Genomic_DNA.
DR   RefSeq; XP_002524040.1; XM_002523994.2.
DR   AlphaFoldDB; B9SDH1; -.
DR   STRING; 3988.B9SDH1; -.
DR   GeneID; 8284298; -.
DR   KEGG; rcu:8284298; -.
DR   eggNOG; KOG0156; Eukaryota.
DR   InParanoid; B9SDH1; -.
DR   OrthoDB; 389111at2759; -.
DR   Proteomes; UP000008311; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IBA:GO_Central.
DR   CDD; cd11075; CYP77_89; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR24298:SF800; CYTOCHROME P450 89A2-RELATED; 1.
DR   PANTHER; PTHR24298; FLAVONOID 3'-MONOOXYGENASE-RELATED; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000461,
KW   ECO:0000313|EMBL:EEF38408.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008311};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   516 AA;  59946 MW;  16C43C01302D3009 CRC64;
     METWFLIIVT LCISSLIKSL FNLFFQSKKQ SLPPGPVKFP IIGNVLWLRK SFFELESIIR
     SLHKELGPMI TLHIGSRPNI FIADRSLAHQ ALVRNGTVFA NRPRAPATTK ITTHNQHSVN
     SAFYGPTWRL LRRNLTSEIL HPSRVKSYSH ARKWVLEILL NRFESQSKSG DPVLVVDNFQ
     YAMFCLLVLM CFGDKLDQKQ IEEIERVERT GLLSIRRFDK LNFMPRLTKI VFRKRWSEFL
     QLQKDREEVL IPLIRARKKV NEEIKSKNCN NEFVLSYVDT LFDLQLPDEK RKLREKEMVA
     LCNEFLNAGT DTTSTALQWV MANLVKYPYI QEKLFMEIKS VVADGEEEVK EDDLQKMSYL
     KAVILEGLRR HPPTHFVLPH AVTEDVVLGK YLVPKNANIN FMVAEMGWDP EVWEEPMAFK
     PERFMGSDSN GEVFDITGSR EIKMMPFGVG RRICPGYGLA LLHLEYFVAN LVWNFQWKAI
     DGDDIDLSEK QQFTIVMKNP LQAHISPRFK RNNHNI
//